Synthesis and characterisation of 2,3a,5,6,7a-pentaacetoxy-octahydro-1H-indene from indan-2-ol

BALCI N., KELEBEKLI L., GÖKSU S., ANIL B., ŞAHİN E.

JOURNAL OF CHEMICAL RESEARCH, sa.4, ss.248-251, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2009
  • Doi Numarası: 10.3184/030823409x430211
  • Dergi Adı: JOURNAL OF CHEMICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.248-251
  • Atatürk Üniversitesi Adresli: Evet

Özet

A synthesis of 2,3a,5,6,7a-pentaacetoxyoctahydro-1H-indene has been achieved starting from indan-2-ol. The Birch reduction of indan-2-ol gave 4,7-dihydro-2-indanol in high yield which when followed by acetylation, resulted in the corresponding acetates. The OsO4 oxidation of the 2-acetoxy-4,7-dihydroindane followed by acetylation furnished the desired pentaacetates in high yield.