Etiological causes in patients with acute urticaria and angioedema: A cross-sectional study.


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Melikoglu M., Pala E., Bayraktar M.

Allergologia et immunopathologia, cilt.50, sa.S Pt 2, ss.15-23, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: S Pt 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.15586/aei.v50isp2.784
  • Dergi Adı: Allergologia et immunopathologia
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, DIALNET
  • Sayfa Sayıları: ss.15-23
  • Anahtar Kelimeler: Angioedema, allergens, exacerbation, symptom, urticaria, blood tests
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Acute urticaria and angioedema are emergency dermatological conditions associated with various etiologic factors. Objective: To determine the etiological causes in patients with acute urticaria and angioedema, and to investigate whether more than one etiological cause was present, along with the patients' laboratory values. Methods: The study was conducted in a tertiary hospital with one center. Etiological causes and laboratory parameters in 284 patients diagnosed with acute urticaria and angioedema were retrospectively studied. Results: A total of 284 patients were included in the study. The mean age of the patients was 42.7 +/- 15.6 years, where 163 (57.4%) were women and 121 (42.6%) were men. Acute urticaria and angioedema occurred together in 149 (52.5%) patients. At least one precipitating factor among the predisposing risk factors was present in 220 (77.5%) patients, and more than one precipitating factor was found in 51 (18%) patients. Medication use was found in 157 (55.3%) patients and infection in 54 (19%). The development of urticaria after food consumption was noted in nine (3.2%) individuals. A history of infection and medication intake was present in 50 (17.6%) patients. A joint history of food consumption and medication intake was present in only one patient. Elevated C-reactive protein level was found in 178 (62.7%) patients and elevated anti-streptolysin O titer in 41 (14.4%) patients. Vitamin B12 deficiency was found in 116 (40.8%) patients and vitamin D deficiency in 254 (89.4%). Conclusion: Acute urticaria and angioedema may occur as a result of multiple etiological factors, in which different triggers may be present simultaneously. (c) 2022 Codon Publications. Published by Codon Publications.