The effectiveness of eugenol against cisplatin-induced ototoxicity A eficácia do eugenol contra a ototoxicidade induzida pela cisplatina

Sakat, Muhammed; Kılıç, Korhan; Akdemir, Serkan; Yıldırım, Serkan; Eser, Gizem; Kızıltunç, Ahmet

doi:10.1016/j.bjorl.2018.07.007

The effectiveness of eugenol against cisplatin-induced ototoxicity A eficácia do eugenol contra a ototoxicidade induzida pela cisplatina

Sakat M. S., Kılıç K., Akdemir F. N. E., Yıldırım S., Eser G., Kızıltunç A.

Brazilian Journal of Otorhinolaryngology, cilt.85, sa.6, ss.766-773, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 85 Sayı: 6
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.bjorl.2018.07.007
Dergi Adı: Brazilian Journal of Otorhinolaryngology
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.766-773
Anahtar Kelimeler: Cisplatin-induced ototoxicity, Eugenol, DPOAE, Oxidative stress, 8-Hydroxy-2 '-deoxyguanosine, ANTIOXIDANT, INHIBITION
Atatürk Üniversitesi Adresli: Evet

Özet

Introduction: Ototoxicity refers to cellular damage or function impairment developing in the inner ear in association with any therapeutic agent or chemical substance, and still represents the principal side-effect restricting the use of cisplatin.