Effect of adenosine triphosphate, benidipine and their combinations on bevacizumab-induced kidney damage in rats.


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Kocaturk H., Bedir F., Turangezli Ö., Arslan R., Çoban T. A., Altuner D., ...More

Advances in clinical and experimental medicine : official organ Wroclaw Medical University, vol.30, 2021 (SCI-Expanded, Scopus)

Abstract

Background. Bevacizumab-induced vascular endothelial growth factor (VEGF) inhibition may lead to a decrease in adenosine triphosphate (ATP) levels, an increase in intracellular Na+ and Ca2+ concentrations and an increase in reactive oxygen species (ROS) generation, as well as to cell damage.