Mitochondrial DNA copy number alterations in familial mediterranean fever patients


Erdem H. B., Ceylan A. C., ŞAHİN İ. F., SEVER-ERDEM Z., CİTLİ Ş., TATAR A.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.119, sa.7, ss.425-428, 2018 (SCI-Expanded) identifier identifier identifier

Özet

OBJECTIVES AND BACKGROUND: Familial Mediterranean Fever (FMF) is characterized by recurrent fever episodes as a result of inflammation of serous membranes. Changes in the number of different mtDNA copy number variations, detected in FMF patients, who developed amyloidosis, might be an important parameter in the understanding of the pathophysiology of the disease.