Akademik Veri Yönetim Sistemi
PHOTOMEDICINE AND LASER SURGERY, cilt.28, sa.1, ss.51-55, 2010 (SCI-Expanded, Scopus)
Background and Objective: To investigate the effect of low-level laser therapy ( LLLT) on healing of skin incisions made using a diode laser in diabetic rats. Material and Methods: Eighteen diabetic Wistar rats were used for this study. One incision was performed on the left side of the dorsum using a diode laser, and the other two incisions were made with a scalpel and diode laser on the right side of each rat. The wound on the left side of each rat received laser stimulation (10 J/cm(2)). The rats were assigned to three experimental groups. Group 1, scalpel (n = 18); Group 2, diode (n = 18); Group 3, diode+biostimulation (n = 18). Results: Reepithelialization was fastest in Group 2 than Group 1 at day 10. The difference between Groups 1 and 3 was also statistically significant in reepithelialization at day 10. There was a significant difference between Groups 1 and 2 and between Groups 2 and 3 in inflammation at day 10. There was no difference between any of the groups in inflammation and reepithelialization at day 20. Conclusions: Scalpel incisions heal more slowly than diode and diode+biostimulation incisions in diabetic rats. We can suggest that diode+biostimulation may produce the least amount of tissue injury, with the fastest resolution of inflammatory response in diabetic rats. Diode laser incision (4 W) with 10-J/cm(2) LLLT seems to have a beneficial effect on skin incisions in diabetic rats.