Akademik Veri Yönetim Sistemi
2nd International Symposium on Functional Nanomaterials in Industrial Applications - Academy-Industry Meet, Preston, Birleşik Krallık, 14 - 16 Nisan 2020, cilt.45, ss.3814-3818
Eleagnus angustifolia has antioxidant, anti-inflammatory, analgesic, anti-cancer, Anti- microbial activity and scar healing properties. Zinc oxide (ZnO) has got much attention in the recently because it is stable under diverse environmental conditions, and fabrication at low temperature. ZnO NPs are believed to be nontoxic, bio-safe, and biocompatible. Recently, in many studies ZnO particles shown antimicrobial activity against both Gram-positive Gram-negative bacteria and even antibacterial activity against spores In the light of information, The aim of this study was to investigate the antimicrobial activity of plant and ZnONPs. In our study, aqueous ethanol extracts of E. angustifolia were prepared and the antimicrobial activity against some pathogenic microorganisms. The MIC was taken as the lowest concentration that inhibited growth after incubation. The test was performed at final concentrations of each extract 12.500;6.250; 3.125; 1.562;781; 390;195;97;48.8; 24.4 mg/mL for microdilution. ZnO. A stock suspension was prepared by resuspending the nanoparticles in double-distilled water to yield a final concentration. Serial 2-fold dilutions of nanoparticles ranging from 0.00625 to 1.6 mg/ml were prepared in a 96-well microtiter plate using MH broth. The MIC values of E. angustifolia ethanol extract for. P. mirabilis, C. albicans, E. faecalis, S. aureus, S. epidermidis, E. coli and P. aeruginosa, A. baumannii were eth were > 12.500, 1.562, 1.562, 3.125, 1.562, > 12.500, > 12.500, > 12.500 mg/ml, respectively. ZnONPs., > 1.6, 0.05, 0.2, 0.05, 1.6, > 1.6. According to the results in our study, the highest effect was observed on gram positive bacteries and yeast. Result of this study suggests that E. angustifolia extracts can be effective in all tested microorganisms. And ZnoNPs effected Gram positive bacteria. Further studies in the effect of different dosages and duration are suggested. Future studies should elucidate the components responsible for antimicrobial activity of these extracts against target cultures.