Akademik Veri Yönetim Sistemi
Journal of Voice, 2025 (SCI-Expanded)
Purpose: The purpose of this study was to investigate the effects of a novel increased vocal demand task (IVDT) performed via forced whispering and examine the usability of a noninvasive assessment method based on biochemical analyses for the assessment of the phonation system. Method: The study was conducted with 30 normophonic women (age range: 20–25). The study included two different IVDTs and a control vocal task (CVT). These tasks were as follows: CVT-habitual, IVDT-loud, and IVDT-whisper. The duration of each task was 90 minutes. The exhaled breath condensate (EBC) method was used to collect biological samples for the assessments, with the following parameters analyzed: nitrate (NO3−) (µM), nitrite (NO2−) (µM), 8-isoprostane (pg/mL), interleukin-6 (IL-6) (pg/mL), and hydrogen peroxide (H2O2) (mmol/L). The parameters examined in the acoustic and electroglottographic (EGG) analyses were the fundamental frequency (fo), amplitude and frequency perturbation, and EGG-contact quotient (CQ) parameters. Perceptual assessment was made using the Borg CR-100 scale. Results: According to the results of the acoustic and EGG assessments, after IVDT-loud, EGG-CQ values decreased, fo increased, and acoustic perturbation values did not change. After IVDT-whisper, EGG-CQ values did not change, fo decreased, and acoustic perturbation values increased. 2 and 4 hours after IVDT-loud, there were significant increases in the values of the biochemical parameters measured by EBC (IL-6, H2O2, and 8-isoprostane) in comparison to the baseline values. According to the perception-based analyses, the Borg CR-100 scores of the participants after IVDT-loud were higher than those obtained after IVDT-whisper. Conclusions: Following the IVDT-loud, which is a high vocal demand task, the presence of increased oxidative stress and inflammatory mediators in the phonation mechanism can be detected using the EBC method. It is seen that IVDT-whisper, which is investigated in the study as a novel IVDT, differs from IVDT-loud in its perceptual and acoustic parameter results.