Endometrial and Ovarian Cancer with MR Imaging Importance of Serum HE4 and CA 125 Levels in the Extent of Disease at Evaluation

Yilmaz E. P., KUMTEPE Y.

Eurasian Journal of Medicine, cilt.48, sa.3, ss.192-198, 2016 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5152/eurasianjmed.2016.0259
  • Dergi Adı: Eurasian Journal of Medicine
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.192-198
  • Anahtar Kelimeler: Ovary, endometrium, cancer, diagnosis, tumor marker, EPIDIDYMIS PROTEIN 4, PROGNOSTIC IMPACT, CARCINOMA, BIOMARKER, PREDICTION, CA125, STAGE, DISTINGUISH, MARKERS, CA-125
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: Currently, no clinically useful tumor marker is available for primary diagnosis in endometrial cancer. Human epididymis protein-4 (HE-4) has high sensitivity and specificity as a tumor marker. Further, HE-4 has been shown to be elevated in early stage endometrial cancer and is more sensitive than CA 125. In our study, CA 125 and HE-4 reputation as a tumor marker for diagnosis of ovarian and endometrial cancer with the use of both the availability and affect the way we investigated the rate of diagnosis.