Endometrial and Ovarian Cancer with MR Imaging Importance of Serum HE4 and CA 125 Levels in the Extent of Disease at Evaluation
Eurasian Journal of Medicine, cilt.48, sa.3, ss.192-198, 2016 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 48 Sayı: 3
- Basım Tarihi: 2016
- Doi Numarası: 10.5152/eurasianjmed.2016.0259
- Dergi Adı: Eurasian Journal of Medicine
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.192-198
- Anahtar Kelimeler: Ovary, endometrium, cancer, diagnosis, tumor marker, EPIDIDYMIS PROTEIN 4, PROGNOSTIC IMPACT, CARCINOMA, BIOMARKER, PREDICTION, CA125, STAGE, DISTINGUISH, MARKERS, CA-125
- Atatürk Üniversitesi Adresli: Evet
Özet
Objective: Currently, no clinically useful tumor marker is available for primary diagnosis in endometrial cancer. Human epididymis protein-4 (HE-4) has high sensitivity and specificity as a tumor marker. Further, HE-4 has been shown to be elevated in early stage endometrial cancer and is more sensitive than CA 125. In our study, CA 125 and HE-4 reputation as a tumor marker for diagnosis of ovarian and endometrial cancer with the use of both the availability and affect the way we investigated the rate of diagnosis.