Impact of Rho-Kinase Inhibitor Hydroxyfasudil in Protamine Sulphate Induced Cystitis Rat Bladder

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Akin Y., BOZKURT A., Erol H. S., Halici M. B., ÇELEBİ F., Kapakin K. A., ...Daha Fazla

LUTS-LOWER URINARY TRACT SYMPTOMS, cilt.7, sa.2, ss.108-114, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/luts.12058
  • Dergi Adı: LUTS-LOWER URINARY TRACT SYMPTOMS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.108-114
  • Anahtar Kelimeler: antioxidants, bladder overactivity, interstitial cystitis, oxidative stress, rho-kinase inhibitors, URINARY GLYCOSAMINOGLYCANS, PAIN, SYMPTOMS, MUSCLE, INJURY, MODEL
  • Atatürk Üniversitesi Adresli: Evet

Özet

ObjectivesThe objective of the present study was to evaluate anti-inflammatory effects of hydroxyfasudil in a protamine sulfate (PS) induced cystitis rat model. Additionally, we investigated prevention of bladder overactivity (BO), and tissue damage in these experiments.