A short synthesis of 4-amino-3-hydroxybutyric acid (GABOB) via allyl cyanide

Mete E., Maras A., Secen H.

RUSSIAN CHEMICAL BULLETIN, cilt.52, sa.8, ss.1879-1881, 2003 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 8
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1023/a:1026045829876
  • Dergi Adı: RUSSIAN CHEMICAL BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1879-1881
  • Atatürk Üniversitesi Adresli: Evet

Özet

4-Amino-3-hydroxybutyric acid was synthesized from allyl cyanide in four steps in an overall yield of 38%. Ultrasonically promoted epoxidation of allyl cyanide with m-chloroperoxy-benzoic acid giving oxiranylacetonitrile was used as a key step.