Determination of 25 (OH) D-3, Iron, Free Iron Binding Capacity and D-Dimer Levels in Calf Diarrhea in Neonatal Period

AKTAŞ M. S., EROĞLU M. S., YANAR K. E., EREN E.

KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.28, sa.4, ss.507-514, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.9775/kvfd.2022.27662
  • Dergi Adı: KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.507-514
  • Anahtar Kelimeler: Calf, D-dimer, Enteritis, Fe, Neonatal, UIBC, Vitamin D, CARDIOMETABOLIC RISK-FACTORS, SERUM IRON, VITAMIN-D, CALVES, PARAMETERS, DIAGNOSIS, BALANCE, SEPSIS
  • Atatürk Üniversitesi Adresli: Evet

Özet

In this study, it was aimed to evaluate the relationship between the clinical course of the disease and hematological data, serum 25-hydroxyvitamin D-3 (25 (OH) D-3), iron (Fe), free iron-binding capacity (UIBC), and D-dimer levels in calves with diarrhea in the neonatal period. Within the scope of the study, 10 healthy calves (group-I) and 30 diarrheal calves in the neonatal period of different races, ages and genders were used. Calves with diarrhea were divided into mild (group-II, n=10), moderate (group-III, n=10) and severe (group-IV, n=10) groups. Blood samples were taken from calves in all groups at once. Hematological analyzes were performed using a veterinary-specific hematology analyzer device. In serum samples, 25 (OH) D-3, Fe and UIBC levels were determined with an autoanalyzer, and D-dimer levels were determined with an automatic immunoassay analyzer. In the hematological analysis, an increase was observed in the number of LYMs (lymphocytes) in group-II (5.04 +/- 1.3) and III (5.2 +/- 3.3) compared to group-I (4.47 +/- 1.2), and a decrease was observed in group IV (2.76 +/- 0.9) (P < 0.05). Fe levels in group-II (59 +/- 56), group III (56 +/- 52) and group IV (72 +/- 63) were found to be decreased compared to group-I (131 +/- 66) (P < 0.05). It was determined that the 25 (OH) D-3 level of group IV (13.4 +/- 8.5) was higher than that of group-I (6.12 +/- 2.73) (P < 0.05). D-dimer levels of group-III (1.15 +/- 1.13) and group-IV (0.96 +/- 0.88) were found to be higher than group-I (0.10 +/- 1.46) (P < 0.05).