The protective effect of aprotinin and alpha-tocopherol on ischemia-reperfusion injury of the rat liver

Polat K., Aydinli B., Polat O., Aydin U., Yazici P., ÖZTÜRK G., ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.40, sa.1, ss.63-68, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.transproceed.2007.11.047
  • Dergi Adı: TRANSPLANTATION PROCEEDINGS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.63-68
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background. Liver injury caused by ischemia-reperfusion (I/R) processes is a complication of hepatic resection surgery and transplantation, particularly using grafts from marginal donors. Despite improvements in organ preservation and advances in surgical techniques, I/R injury remains a significant clinical problem. In this study, we investigated whether aprotinin provided protection against the adverse effects of I/R injury in liver tissue.