Protective Effect of Carvacrol against Paclitaxel-Induced Ototoxicity in Rat Model

Atalay F., Tatar A., Dincer B., Gündoğdu B., Koycegiz S.

TURKISH ARCHIVES OF OTORHINOLARYNGOLOGY, cilt.58, sa.4, ss.241-248, 2020 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 58 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/tao.2020.5714
  • Dergi Adı: TURKISH ARCHIVES OF OTORHINOLARYNGOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.241-248
  • Anahtar Kelimeler: Carvacrol, ototoxicity, oxidative stress, paclitaxel, animal experimentation, CISPLATIN OTOTOXICITY, INDUCED APOPTOSIS, CANCER, TISSUE, BREAST, ASSAY
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: This study aimed to explore whether carvacrol (CV) had a protective effect on paclitaxel-induced ototoxicity from biochemical, functional, and histopathological perspectives.