Climate and geography play a significant role in the mobility of people, affecting their economic pursuits, eating and clothing habits, architectural construction techniques, and the selection of building materials. In this context, the geography-climate conditions in which civilizations are born and flourish become the prevailing elements that determine their socio-cultural characteristics. Within this scope, this paper explores and presents a brief evaluation of the Kura-Araxes settlements in the Upper Euphrates-Malatya Basin through the key mounds. The earliest findings regarding the urbanism of the archaeological settlements in the region date back to the 4th millennium. However, as the Keban and Karakaya Dams submerged the archaeological site, general assessments about these settlements could only be made with the available archeological data afterwards. Besides, since the rescue excavations were carried out swiftly, there was confusion in the evaluation of the results and the comparison of the data. Moreover, as the settlements have not been completely unearthed and the inconsistency experienced in the chronological plane still exists, new evaluations are needed about these settlements. To this end, landscape analysis of the Kura-Araxes settlements, which are among the noteworthy mounds of different scales, was conducted, and the results regarding the geographical distribution problematic in the location selection of the settlements were analyzed. In addition, even if it was incomplete, the significant data about the architectural texture of the settlements were evaluated on the common denominator.