Relation of Neutrophil to Lymphocyte Ratio With the Presence and Severity of Stable Coronary Artery Disease
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, cilt.20, sa.5, ss.473-477, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 5
- Basım Tarihi: 2014
- Doi Numarası: 10.1177/1076029612473517
- Dergi Adı: CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.473-477
- Anahtar Kelimeler: neutrophil/lymphocyte ratio, stable coronary artery disease, SYNTAX score, INTRAUTERINE GROWTH RESTRICTION, ELEVATION MYOCARDIAL-INFARCTION, LONG-TERM MORTALITY, C-REACTIVE PROTEIN, INFLAMMATION, ATHEROSCLEROSIS, ASSOCIATION, PREDICTION, OUTCOMES, MARKERS
- Atatürk Üniversitesi Adresli: Evet
Özet
Objectives: We examined the association between neutrophil to lymphocyte ratio (NLR) and the complexity of coronary artery disease assessed by SYNTAX score (SS). Methods: The study population included patients with chest pain who had undergone coronary angiography for stable angina pectoris. Patients were classified depending on whether the SS was 0 or SS > 0. Results: Left ventricular ejection fraction, estimated glomerular filtration rate, and NLR were found to be the independent predictors of high SS in multivariate analysis. The area under the receiver-operating curve of NLR was 0.72 (0.65-0.80, P <.001) for predicting high SS. The optimal cutoff value of NLR to predict high SS was 2.7 (sensitivity of 72% and a specificity of 61%). There was a significant correlation between NLR ratio and continuous SS (r =.552, P <.001). Conclusion: The NLR is a readily measurable systemic inflammatory marker and is associated with both the presence and the complexity of coronary artery disease.