Cycloaddition Reactions of Benzonorbornadiene and Homonorbornadiene: New Isoxazoline and Pyridazine Derivatives
JOURNAL OF HETEROCYCLIC CHEMISTRY, cilt.55, sa.8, ss.1917-1925, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 55 Sayı: 8
- Basım Tarihi: 2018
- Doi Numarası: 10.1002/jhet.3229
- Dergi Adı: JOURNAL OF HETEROCYCLIC CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1917-1925
- Atatürk Üniversitesi Adresli: Evet
Özet
Ten new isoxazoline derivatives were synthesized from the reactions of benzonorbornadiene and homonorbornadiene derivatives with nitrile oxides formed from benzaldehyde and 4-substituted benzaldehyde. Two new pyridazine derivatives were also synthesized from the reaction of the homonorbornadiene derivatives with 3,6-di (2-pyridyl)-s-tetrazine. It was seen that all cycloaddition reactions were realized as exo selectivity. Finally, -Gauche effect in the isoxazoline derivatives was discussed.