Cycloaddition Reactions of Benzonorbornadiene and Homonorbornadiene: New Isoxazoline and Pyridazine Derivatives

Adiloglu Y., ŞAHİN E., Tutar A., MENZEK A.

JOURNAL OF HETEROCYCLIC CHEMISTRY, cilt.55, sa.8, ss.1917-1925, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 8
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1002/jhet.3229
  • Dergi Adı: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1917-1925
  • Atatürk Üniversitesi Adresli: Evet

Özet

Ten new isoxazoline derivatives were synthesized from the reactions of benzonorbornadiene and homonorbornadiene derivatives with nitrile oxides formed from benzaldehyde and 4-substituted benzaldehyde. Two new pyridazine derivatives were also synthesized from the reaction of the homonorbornadiene derivatives with 3,6-di (2-pyridyl)-s-tetrazine. It was seen that all cycloaddition reactions were realized as exo selectivity. Finally, -Gauche effect in the isoxazoline derivatives was discussed.