Detection of human cytomegalovirus and Epstein-Barr Virus in symptomatic and asymptomatic apical periodontitis lesions by real-time PCR

Ozbek S., ÖZBEK A., YAVUZ M. S.

MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL, cilt.18, sa.5, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 5
  • Basım Tarihi: 2013
  • Doi Numarası: 10.4317/medoral.18905
  • Dergi Adı: MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Human cytomegalovirus, Epstein-Barr Virus, apical periodontitis, Polymerase chain reaction method, PERIAPICAL PATHOSIS, HERPESVIRUSES, TRANSCRIPTION, INFECTIONS, IDENTIFICATION, DIAGNOSIS, DISEASES, TEETH
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objectives: Recent studies have investigated the occurrence of human cytomegalovirus and Epstein-Barr Virus in samples from apical periodontitis lesions and a role in the pathogenesis of this disease has been suggested. Because genotype distribution and seroprevalence of EBV and HCMV differ among populations, it is important to determine the presence of these viruses in endodontic periapical lesions of different populations. The aims of this study were to determine the presence of HCMV and EBV DNAs in samples from Turkish patients with symptomatic and asymptomatic apical periodontitis lesions using real-time polymerase chain reaction method and to evaluate their presence in both symptomatic and asymptomatic apical periodontitis lesions.