Ankara Medical Journal, cilt.22, sa.3, ss.370-380, 2022 (Scopus)
© 2022 Authors.Objectives: This study investigated the effect of acupuncture treatment on attack frequency, pain intensity, and disability in patients with migraine without aura that received prophylaxis treatment. Materials and Methods: Eighty-four patients with migraine without aura were randomized to the intervention group (IG; n=42) and control group (CG; n=42). IG received 12 sessions of Acupuncture in addition to prophylaxis treatment. CG received only prophylaxis treatment. The primary outcome measures were monthly attack frequency, duration of attacks and pain severity during attacks. The secondary outcome measure included a change of Migraine Disability Assessment (MIDAS) scores from baseline to endpoints. All participants were followed up for three months. Results: A total of 80 participants completed the study. There were no statistically significant differences between the IG and CG for either socio-demographic features or the outcome measures at baseline. VAS score decreased from 8.8±0.9 to 3.9±1.5 in IG, while it decreased from 8.7±0.8 to 4.4±2.4 in CG (p=0.001). After three months mean monthly attack frequency decreased from 7.2±3.0 to 3.3±2.3 in IG, while it decreased from 6.3±3.3 to 4.4±2.4 in CG (p=0.040). The mean duration of attacks was 12.1± 2.6 hours before intervention; it decreased to 3.1±1.7 hours in IG (p=0.002). There was a significantly higher proportion of participants in IG who had MIDAS Grade 2 compared to those with CG (42.50% versus 2.50%) at the end of the study (p=0.001). Conclusion: Acupuncture may be suggested as a complementary treatment option to optimize the clinical management of patients with migraine without aura via decreasing attack frequency and pain severity, also improving disability.