Akademik Veri Yönetim Sistemi
12. International Conference on Agriculture, Animal Science & Rural Development, Ordu, Türkiye, 6 - 08 Temmuz 2023, ss.904-913
Milk and dairy products, which are an important source of nutrition, can sometimes be contaminated with harmful compounds such as heavy metals, pesticides, veterinary drugs, and dioxins. Dioxins, which pose significant risks to human and animal health by being included in the food chain, are formed as a result of exposure of substances containing chlorine or bromine to high temperatures. Dioxins, which are poorly soluble in water, are soluble in lipids and non-polar organic solvents and can be degraded in the absence or presence of oxygen. Dioxins, which are highly resistant to metabolic degradation in the body, have a long half-life under natural environmental conditions. As a source of dioxin; exhaust gases from vehicles using leaded fuel, paper packaging in contact with food, preparations used in cosmetics, dentistry and medicine, chemical factories, wood and waste incineration processes, machinery, and engine oils can be given as examples. Dioxins can enter the human body, primarily through the respiratory tract, from meat and milk from animals fed with dioxin-contaminated feed and from fish and other aquaculture products grown in contaminated waters. Dioxins, which are mostly taken into the body with fatty foods, show different accumulation and toxicity depending on metabolism. Dioxins, which inhibit protein synthesis in the cell by forming a complex with DNA in the cytoplasm, bind to Arh receptors and cause DNA mutation. To protect against dioxin toxicity, it is necessary to classify waste and apply appropriate waste disposal processes for each category, to use unbleached or chlorine-free paper products, to minimize the use of low-quality plastic packaging, to prevent food contact, to choose low-fat products instead of full-fat ones, to construct industrial facilities away from agricultural areas, and to utilize effective filters in vehicles and factories. This review study provides detailed information about the components of dioxins, sources and contamination reasons of dioxins, the impact of dioxins on human health, and measures that can be taken to protect against dioxin toxicity.