Paracetamol-induced nephrotoxicity and oxidative stress in rats: the protective role of Nigella sativa.

CANAYAKIN D., BAYIR Y., BAYGUTALP N., KARAOGLAN E., Atmaca H. T., OZGERIS F. B. K., ...Daha Fazla

Pharmaceutical biology, cilt.54, sa.10, ss.2082-91, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 10
  • Basım Tarihi: 2016
  • Doi Numarası: 10.3109/13880209.2016.1145701
  • Dergi Adı: Pharmaceutical biology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2082-91
  • Anahtar Kelimeler: Glutathione, kidney, malondialdehyde, superoxide dismutase, ACUTE-RENAL-FAILURE, CHEMICAL-COMPOSITION, POSSIBLE MECHANISM, N-ACETYLCYSTEINE, ACETAMINOPHEN, LIVER, THYMOQUINONE, KIDNEY, ANTIOXIDANT, TOXICITY
  • Atatürk Üniversitesi Adresli: Evet

Özet

Context Nigella sativa L. (Ranunculaceae) (NS) is traditionally used to treat many conditions such as inflammation. Objective This study evaluates the effects of NS seeds ethanol extract in paracetamol-induced acute nephrotoxicity in rats.