GC-MS Determination of Diclofenac in Human Plasma
CHROMATOGRAPHIA, cilt.71, ss.549-551, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 71
- Basım Tarihi: 2010
- Doi Numarası: 10.1365/s10337-010-1479-z
- Dergi Adı: CHROMATOGRAPHIA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.549-551
- Anahtar Kelimeler: Gas chromatography-mass spectrometry, Diclofenac in human, Plasma, LIQUID-CHROMATOGRAPHIC DETERMINATION, ELECTROCHEMICAL DETECTION, METABOLITES, URINE, BIOAVAILABILITY, FLUID
- Atatürk Üniversitesi Adresli: Evet
Özet
The aim of the present study was to develop a procedure based on gas chromatography-mass spectrometry for the determination of diclofenac in human plasma. This assay was successfully applied in Turkey to healthy volunteers after an oral administration of 50 mg diclofenac.