Akademik Veri Yönetim Sistemi
2nd International and 13th National Veterinary Internal Medicine Congress, Ankara, Türkiye, 11 - 13 Ekim 2019, Ankara, Türkiye, 11 - 13 Ekim 2019, ss.204
Salicylic acid is a metabolite of acetylsalicylic acid (Aspirin) and is responsible for the anti-inflammatory effect of
aspirin. Although the antiplatelet effect is specific to aspirin, salicylic acid and aspirin have similar properties. In this
case report, it was aimed to report acute salicylic acid intoxication in a dog. The material of this case consisted of an
11.5-month-old and 20 kg live weight Game dog male with complaints of inability to stand up, fatigue, tachypnea and
high fever. In the anamnesis, it was learned that the dog ate approximately half of the 80 grams of “Biyoteknik Salisil”
ointment containing salicylic acid 6 hours before coming to the hospital and the clinical symptoms started to take
shape 3 hours later. Salicylic acid toxicity was observed in the dog as a result of this situation which corresponds to
salicylic acid consumption at 2000 mg/kg dose. Clinical examination of the dog revealed hyperthermia (39.9 C),
tachypnea (56/min), mild wilt in the conjunctival mucosa, weakness, reluctance to walk, and paresis on the hind legs.
In the hemogram findings, erythrocyte, haemoglobin and hematocrit parameters were at the baseline level,
neutrophilic leukocytosis was observed and thrombocyte count was normal. Lactated Ringer solution (40 ml/kg/day,
iv., 3 days), Ranitidine (2 mg/kg, twice daily, iv., 7 days) and sulfadoxine-trimethoprim (500 mg/kg sulfadoxin+100
mg/kg trimethoprim, once daily, im., 3 days) was implemented. As the treatment proceeded, it was noticed that the
dog started to walk, general medical condition bettered, the level of leucocyte turned to the normal level and the
levels of erythrocyte, haemoglobin, and hematocrit increased. In conclusion, it was concluded that salicylic acid
toxicity in dogs had similar but milder clinical findings with aspirin toxicity and that treatment protocols applied in
aspirin toxicity could be applied in salicylic acid toxicity