An ancient plant Lawsonia inermis (henna): Determination of in vitro antifungal activity against dermatophytes species

GÖZÜBÜYÜK S. G., AKTAŞ A. E., YİGİT N.

JOURNAL DE MYCOLOGIE MEDICALE, cilt.24, sa.4, ss.313-318, 2014 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.mycmed.2014.07.002
  • Dergi Adı: JOURNAL DE MYCOLOGIE MEDICALE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.313-318
  • Anahtar Kelimeler: Henna paste, Dermatophytes, Antifungal activity, EXTRACTS, L.
  • Atatürk Üniversitesi Adresli: Evet

Özet

World is endowed with a rich wealth of medicinal plants. There is a widespread belief that green medicines are healthier and more harmless or safer than synthetic ones. Medicinal plants have been used to cure a number of diseases. The ancient plant Lawsonia inermis or henna is used as medicinal plant because of its attributed strong fungicidal, anti-inflammatory, analgesic, antibacterial, virucidal, antiparasitic, antiamoebiasis, astringent, antihemorrhagic, hypotensive, sedative, anticancer effect and possible anti-sweating properties. In this study, we investigated antifungal activity of L. inermis against clinical dermatophytes species. This study was carried out using 70 clinical isolates of dermatophytes representing six different species; 44 Trichophyton rubrum, 8 Trichophyton mentagrophytes, 6 Microsporum canis, 6 Trichophyton tonsurans, 4 Epidermophyton floccosum, and 2 Trichophyton violaceum. The antifungal activity of L. inermis (henna) was determined by agar diffusion method and henna was used as paste form. Henna paste showed the high antifungal activity against all dermatophytes species (20 to 50 mm inhibition zone). (C) 2014 Elsevier Masson SAS. All rights reserved.