Recent Advances in Nickel Catalysts for Sonogashira Coupling


Payamifar S., Etminan P., Poursattar Marjani A.

ChemistryOpen, cilt.15, sa.5, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 15 Sayı: 5
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1002/open.70217
  • Dergi Adı: ChemistryOpen
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, Compendex, EMBASE, MEDLINE, Directory of Open Access Journals, Academic Search Ultimate (EBSCO), Materials Science & Engineering Collection (ProQuest), Technology Collection (ProQuest)
  • Anahtar Kelimeler: aryl halides, coupling reaction, nickel catalyst, sonogashira reaction, terminal alkynes
  • Atatürk Üniversitesi Adresli: Evet

Özet

The Sonogashira coupling, catalyzed by transition metals, has become a valuable method for forming carbon-carbon bonds. While palladium-copper was originally recognized as the most effective catalyst for this transformation, recent advances have highlighted the growing prominence of nickel-catalyzed Sonogashira reactions. Nickel has gained considerable interest due to its lower cost and more environmentally friendly profile compared to palladium. This review focuses on recent progress in nickel-catalyzed Sonogashira coupling, surveying studies published between 2021 and 2025.