Zwitterionic Salts from the Reaction of Symmetrical and Unsymmetrical (thio)Barbituric Acids with 2-Pyridinecarbaldehyde under Solvent-free Condition
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, cilt.59, sa.12, ss.1561-1566, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 59 Sayı: 12
- Basım Tarihi: 2012
- Doi Numarası: 10.1002/jccs.201200082
- Dergi Adı: JOURNAL OF THE CHINESE CHEMICAL SOCIETY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1561-1566
- Atatürk Üniversitesi Adresli: Evet
Özet
A simple and efficient synthesis for the preparation of unusual charge-separated pyridinium (thio)barbiturate zwitterion derivatives was achieved via a one-pot reaction of (thio)barbituric acid derivatives and 2-pyridinecarbaldehyde under solvent-free condition and also in methanol under refluxing. The structure of the compounds was confirmed by (HNMR)-H-1, (CNMR)-C-13, FT-IR, mass and X-ray analysis. The mechanism of the formation is discussed. Instead, no related pyridinium zwitterion was afforded from the reaction between dimedone and 2-pyridinecarbaldehyde under the same conditions and its xanthene derivative was obtained.