Analysis of Phenolic Compounds by LC-HRMS and Determination of Antioxidant and Enzyme Inhibitory Properties of Verbascum speciousum Schrad

Creative Commons License

Kızıltaş H., Bingol Z., Goren A. C., Alwasel S. H., GÜLÇİN İ.

RECORDS OF NATURAL PRODUCTS, cilt.17, ss.485-500, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17
  • Basım Tarihi: 2023
  • Doi Numarası: 10.25135/rnp.370.2210.2598
  • Dergi Adı: RECORDS OF NATURAL PRODUCTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, ABI/INFORM, CAB Abstracts, EMBASE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.485-500
  • Anahtar Kelimeler: Verbascum speciosum, antioxidant activity, reducing power, radical scavenging, enzyme inhibition, IN-VITRO ANTIOXIDANT, RADICAL SCAVENGING ACTIVITIES, CARBONIC-ANHYDRASE, ANTIRADICAL ACTIVITIES, CRYSTAL-STRUCTURE, CAFFEIC ACID, ACETYLCHOLINESTERASE, DERIVATIVES, EXTRACT, BUTYRYLCHOLINESTERASE
  • Atatürk Üniversitesi Adresli: Evet

Özet

Studies have shown an inverse correlation among age-related illnesses like coronary heart disease and cancer and intake of fruit and vegetable. Given the probable health benefits of natural antioxidants from plants, research on them has increased. Verbascum L is a large genus of Scrophulariaceae family and 323species distributed worldwide. Since Verbascum L. species are plants that grown in many regions of the Turkiye and used in folk medicine, it is important to evaluate the biological activity of these species. In this study antioxidant properties of Verbascum speciosum Schrad. were investigated. The antioxidant capacities of water and ethanolbased extracts obtained from air parts were evaluated with Fe3+ reducing, CUPRAC, FRAP, DPPH. and ABTS(center dot+) scavenging antioxidant methods. Extracts were examined to determine their AChE, alpha-glycosidase and a-amylase enzyme inhibitions also. This investigation could be a basis for further phytochemical investigations of Verbascum speciosum Schrad.