PROTECTIVE ROLE OF INTERFERON-B IN EXPERIMENTALLY INDUCED PERIPHERAL NERVE INJURY IN RATS

ÇAKIR M., Zengin S., ÇALIKOĞLU Ç., AKPINAR E., DEMİR R., ÜNAL D., ...Daha Fazla

ACTA MEDICA MEDITERRANEA, cilt.31, sa.5, ss.973-979, 2015 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 5
  • Basım Tarihi: 2015
  • Dergi Adı: ACTA MEDICA MEDITERRANEA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.973-979
  • Atatürk Üniversitesi Adresli: Evet

Özet

Introduction: Interferon-beta (IFN-beta) has been used for the treatment of multiple sclerosis, because of its immunomodulatory activity. IFN-beta can also improve nerve regeneration after crush injuries. We aimed to investigate the potential of using IFN-beta to treat peripheral nerve injury and the role of pro-inflammatory mediators and apoptosis in the effect of IFN-beta.