Comparison of intradermal sterile water injection and dexketoprofen trometamol in pain management of renal colic patients


Senol A., Arslan S., Can N. O., TEKİN E., Doru H. I.

American Journal of Emergency Medicine, cilt.96, ss.1-5, 2025 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 96
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1016/j.ajem.2025.06.005
  • Dergi Adı: American Journal of Emergency Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1-5
  • Anahtar Kelimeler: Dexketoprofen, Renal colic, Sterile water injection
  • Atatürk Üniversitesi Adresli: Evet

Özet

Aim: In our study, we planned to investigate the efficacy of intradermal sterile water injections (ISWI) in the pain management of patients admitted to the emergency department due to renal colic. We also aimed to investigate patient satisfaction and reduce the use of opioid drugs with this method. Patients and methods: A randomized controlled trial was conducted with 100 patients who presented with renal colic. Patients were divided into two groups: Group 1 received 50 mg of intravenous dexketoprofen trometamol, while Group 2 received dexketoprofen trometamol along with ISWI administered to four predetermined dermatomes (T11–L4). Pain levels were assessed using the Visual Analog Scale (VAS) at baseline and at 5, 10, 15, and 30 min post-treatment. Rescue analgesia requirements were also recorded. The primary outcome was the change in VAS pain score from baseline to 30 min after treatment. Findings: ISWI combined with dexketoprofen trometamol significantly reduced VAS scores compared to dexketoprofen trometamol alone (p < 0.05). The study was not registered, and the outcome assessment was not blinded. CONSORT methodology was not fully followed. These limitations need to be considered when interpreting the results. Conclusion: The combination of ISWI and dexketoprofen trometamol provides superior pain relief and reduces the need for rescue analgesia in patients with renal colic compared to dexketoprofen trometamol alone. However, because of the limitations mentioned above, no definitive conclusions can be drawn from this study.