Ethanol Extract of Myrtle (Myrtus communis L.) Berries as a Remedy for Streptozotocin-Induced Oxidative Stress in Rats

AĞGÜL A. G., Demir G. M., GÜLABOĞLU M.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, cilt.194, sa.4, ss.1645-1658, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 194 Sayı: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1007/s12010-021-03753-z
  • Dergi Adı: APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Compendex, EMBASE, Food Science & Technology Abstracts, MEDLINE, Pollution Abstracts, Veterinary Science Database
  • Sayfa Sayıları: ss.1645-1658
  • Anahtar Kelimeler: Antioxidant, Ethanol extract, Myrtus communis, Oxidative stress, Streptozotocin, ANTIOXIDANT ACTIVITIES, AQUEOUS EXTRACT, ESSENTIAL OILS, ALLOXAN, INHIBITION, CAPACITY, LEAVES, LEAF
  • Atatürk Üniversitesi Adresli: Evet

Özet

Streptozotocin (STZ) is an antitumor antibiotic indicating in the treatment of metastatic islet cell carcinoma of the pancreas. It is also used as a tool to create experimental diabetes models. The STZ exposure at a high dose causes severe damage to cells of humans and other mammals. The goal of the present study was to assess the protective effects of the ethanol extract of the Myrtle (Myrtus communis L.) berries, which is a well-known medicinal plant due to its rich phenolic content and beneficial effects on health, against STZ-induced oxidative stress in the diabetic rats.