Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties

GÖCER H., Gulcin I.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, cilt.62, sa.8, ss.821-825, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 8
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3109/09637486.2011.585963
  • Dergi Adı: INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.821-825
  • Anahtar Kelimeler: Caffeic acid phenethyl ester, antioxidant activity, radical scavenging, PROPOLIS, ABILITY
  • Atatürk Üniversitesi Adresli: Evet

Özet

Caffeic acid phenethyl ester (CAPE), a plant polyphenolic concentrated in honeybee propolis, has been found to be biologically active in a variety of pathways. The aim of this study was to determine the antioxidant activity of CAPE using different methods such as total antioxidant activity by the thiocyanate method, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid radicals, 1,1-diphenyl-2-picryl-hydrazyl free radicals, N,N-dimethyl-p-phenylenediamine dihydrochloride radicals and superoxide anion radicals scavenging activities, reducing power and ferrous ions (Fe2+) chelating activities. CAPE showed 97.9% inhibition on lipid peroxidation of linoleic acid emulsion. On the other hand, butylated hydroxyanisole, butylated hydroxytoluene, a-tocopherol and trolox indicated an inhibition of 87.3, 97.6, 75.3 and 90.3% on peroxidation in the same system, respectively.