Metrikler
Yayın
284
Açık Erişim
13
BM Sürdürülebilir Kalkınma Amaçları
Eğitim Bilgileri
1991 - 1996
1991 - 1996Doktora
Ege Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya, Türkiye
1989 - 1991
1989 - 1991Yüksek Lisans
Ege Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya, Türkiye
1984 - 1988
1984 - 1988Lisans
Ege Üniversitesi, Eczacılık Fakültesi, Türkiye
Yaptığı Tezler
1996
1996Doktora
Antineoplastik bileşikler olarak tasarlanan Mannich bazları ve izosterik piperidinol türevleri üzerinde araştırmalar
Ege Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya
1991
1991Yüksek Lisans
Antineoplastik bileşikler olarak tasarlanan Stiril ketonlar ve onların amino türevleri üzerinde araştırmalar
Ege Üniversitesi, Eczacılık Fakültesi, Farmasötik Kimya
Yabancı Diller
C1 İleri
C1 İleriİngilizce
Araştırma Alanları
Sağlık Bilimleri
Eczacılık
Meslek Bilimleri
Farmasötik Kimya
Akademik Ünvanlar / Görevler
2008 - Devam Ediyor
2008 - Devam EdiyorProf. Dr.
Atatürk Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Yönetimsel Görevler
2004 - 2019
2004 - 2019Bölüm Başkanı
Atatürk Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
2008 - 2013
2008 - 2013Dekan Yardımcısı
Atatürk Üniversitesi
Verdiği Dersler
Doktora
Doktora
İlaç Tasarımı I
İleri Organik Kimya I
Danışmanlık
Tıbbi Kimya I
İlaç Tasarımı II
Organik Spektroskopik Analiz
Uzmanlık Alan Dersi VIII
Uzmanlık Alan Dersi I
Lisans
Lisans
Araştırma Projesi II
Farmasötik Kimya IV
Farmasötik Kimya I
Literatür Araştırma ve İnceleme
Farmasötik Kimya III
Eczacılık Alanında Çeviriler
Farmasötik Kimya II
İlaç ve Laboratuvar Bilgisine Giriş
Farmasötik Kimya Lab III
Farmasötik Kimya Lab I
Farmasötik Kimya Lab IV
Farmasötik Kimya Lab II
Mezuniyet Projesi I
Mesleki Latince
Yönetilen Tezler
2021
2021Doktora
Sülfonamit artığı taşıyan yeni pirazol türevlerinin sentezi ve sitotoksik etkilerinin araştırılması
Gül H. İ. (Danışman)
D.ÖZMEN(Öğrenci)
2018
2018Doktora
. Pirazol-Benzensülfonamit Türevi Bileşiklerin Tasarımı, Sentezi, Kimyasal Yapılarının Aydınlatılması Ve Biyoaktiviteleri
GÜL H. İ.
C.YAMALI(Öğrenci)
2016
2016Doktora
İndanon Ve İndandionlardan Türevlenen Potansiyel Biyoaktif Bileşiklerin Sentezi Ve Biyoaktiviteleri
GÜL H. İ.
M.TUĞRAK(Öğrenci)
2016
2016Yüksek Lisans
5-Metil-2-İzopropilfenol'ün Mannich Bazlarının Sentezi Ve Sitotoksik Aktivitelerinin İncelenmesi
GÜL H. İ.
A.TUĞÇE(Öğrenci)
2016
2016Yüksek Lisans
4-[5-(2,4/3,4-dimetoksifenil)-3-sübstitüefenil- 4,5-dihidro-1h-pirazol-1-il] benzensülfonamit türevlerinin sentezi ve sitotoksik aktivitelerinin incelenmesi
GÜL H. İ.
D.ÖZMEN(Öğrenci)
2013
2013Yüksek Lisans
1-Aril--3-Dibenzilamino-Propan-1-On Hidroklorür Tipi Mannich Bazları Üzerinde Çalışmalar
GÜL H. İ.
A.TÜRÜT(Öğrenci)
2013
2013Yüksek Lisans
1-[3,5-Bis (Aminometil)-4-Hidroksi-Fenil]-3-(Aril) - 2-Propen-1-On’ Ların Sentezi, Sitotoksisitesi, Selektivite İndekslerinin Araştırılması
GÜL H. İ.
F.YEŞİLYURT(Öğrenci)
2013
2013Yüksek Lisans
Potansiyel Biyoaktif Bileşikler Olan 2-(4-Hidroksifenil)Benzimidazol Mannich Bazları Üzerinde Çalışmalar
GÜL H. İ.
Z.YAZICI(Öğrenci)
2013
2013Yüksek Lisans
1-Aril-3-Fenetilamino-1-Propanon Hidroklorür Tipi Mono Mannich Bazlarının Konvansiyonel Yöntem Ve Mikrodalga Yöntemi İle Sentezi Ve Sentezlenen Bileşikler Üzerinde Stabilite Çalışmaları
GÜL H. İ.
S.PEKCAN(Öğrenci)
2012
2012Yüksek Lisans
1-Aril-3-(2-Hidroksietiltiyo)-1-Propanonların Sentezi Ve Sitotoksite Selektivite İndeksinin Ve Olası Etki Mekanizmasınını Araştırılması
GÜL H. İ.
E.ÜNLÜER(Öğrenci)
2011
2011Yüksek Lisans
Potansiyel Biyoaktif Moleküller Olan 1-Aril-3-Benzilamino-1-Propanon Hidroklorürlerin Sentezlenmesi
GÜL H. İ.
E.KARABİBER(Öğrenci)
2011
2011Doktora
Heterosiklik Şalkon Anologlarının Mannich Bazlarının Sentezi Ve Biyolojik Aktivitesinin Değerlendirilmesi
GÜL H. İ.
S.BİLGİNER(Öğrenci)
2011
2011Yüksek Lisans
1-Aril-3-Amino-1-Propanon Hidroklorür Tipi Mono Mannich Bazlarının Konvansiyonel Yöntem Ve Mikrodalga Yöntemi İle Sentezi Ve Sentezlenen Bileşikler Üzerinde Stabilite Çalışmaları
GÜL H. İ. (Danışman)
E.TUTAR(Öğrenci)
2011
2011Yüksek Lisans
1-Aril-3-Morfolino-1-Propanon Hidroklorür Kimyasal Yapısına Sahip Bileşiklerin Mikrodalga Ve Konvansiyonel Yöntem İle Sentezi
GÜL H. İ.
G.UÇAR(Öğrenci)
2011
2011Yüksek Lisans
1-Aril-3-Piperidino-1-Propanon Hidroklorür Kimyasal Yapısına Sahip Bileşiklerin Mikrodalga Ve Konvansiyonel Yöntem İle Sentezi
GÜL H. İ.
A.DEMİRTAŞ(Öğrenci)
2011
2011Yüksek Lisans
1-Aril-2-(4-Metilpiperazino)Metil-2-Propen-1-On Dihidroklorür Kimyasal Yapısına Sahip Mannich Bazlarının Mikrodalga Yöntemi İle Sentezi Ve Antifungal Aktivitesinin Araştırılması
GÜL H. İ.
M.KOCA(Öğrenci)
2011
2011Yüksek Lisans
1-Aril-2-(N-Metilpiperazinometil)-2-Propen-1-On Kimyasal Yapısına Sahip Bileşiklerin Klasik Mannich Reaksiyonu İle Sentezi Ve Biyolojik Aktivitesinin Araştırılması
GÜL H. İ.
M.TUĞRAK(Öğrenci)
2010
2010Yüksek Lisans
1-Aril-2-Morfolinometil-2-Propen-1-On Yapısındaki Bileşiklerin Sentezi Ve Antifungal Etkilernin Araştırılması
GÜL H. İ.
S.Emre(Öğrenci)
2009
2009Doktora
N,N’-Bis(3-Amino-1-Aril-Propiliden)Hidrazin Dihidroklorür Tipi Bazı Bileşiklerin Sentezi Ve Sitotoksik Aktivitesinin Değerlendirilmesi
GÜL H. İ.
K.KÜÇÜKOĞLU(Öğrenci)
2009
2009Doktora
3-Aril-1-(4-Hidroksifenil)-2-Propen-1-On Ve 1,5-Diaril-Penta-1,4-Dien-3-On Türevi Bileşiklerin Ve Onların Aminometil Türevlerinin Sentezi Ve Sitotoksik Aktivitelerinin Değerlendirilmesi
GÜL H. İ.
K.Özden(Öğrenci)
2008
2008Yüksek Lisans
1-Aril-3-Fenetilamino-1-Propanon Hidroklorür Ve 4-Aril-3-Aroil-1-Fenetil-4-Piperidinol Kimyasal Yapısına Sahip Bileşiklerin Sentezi Ve Antifungal Etkilerinin Araştırılması.
GÜL H. İ.
C.Özelgül(Öğrenci)
2005
2005Yüksek Lisans
Şalkonların Ve Onların Mannich Bazlarının Sentezi Ve Onların Antikonvülzan, Sitotoksik Ve Antimikrobiyal Etkilerinin Araştırılması.
GÜL H. İ.
K.Özden(Öğrenci)
Makaleler
Tümü (145)
SCI-E, SSCI, AHCI (130)
SCI-E, SSCI, AHCI, ESCI (135)
ESCI (6)
Scopus (133)
TRDizin (13)
Diğer Yayınlar (5)
2026
20261. Design, synthesis and QSAR-based antitumor signaling pathway analysis of pyrazoline- benzenesulfonamides mediated by cytostatic G1 arrest
Ozgun D. O., METE E., YAMALI C., KAZAZ C., Sakagami H., Amano S., et al.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1350, 2026 (SCI-Expanded, Scopus)
2025
20252. Indanone-based Mannich bases: Design, synthesis, in-silico molecular docking, ADME predictions and biological evaluation including carbonic anhydrases, acetylcholinesterase inhibition and cytotoxicities
Sakarya M. T., GÜL H. İ., Sakagami H., SERT Y., Taslimi P., GÜLÇİN İ.
Archives of Biochemistry and Biophysics
, cilt.771, 2025 (SCI-Expanded, Scopus)
2025
20253. Molecular Docking Studies and Biological Activities of Chalcones Targeting Acetylcholinesterase, and Carbonic Anhydrase Isoenzymes
Tuğrak Sakarya M., Gül H. İ., Sert Y., Akincioglu H., Gülçin İ., Gül M.
KSU TARIM VE DOGA DERGISI-KSU JOURNAL OF AGRICULTURE AND NATURE
, sa.2, ss.335-350, 2025 (ESCI, TRDizin)
2025
20254. Synthesis, Bioactivities, and in Silico Studies of Novel Benzo[d][1,3]Dioxole-Based Pyrazoline Sulfonamides
Tugrak Sakarya M., GÜL H. İ., YAMALI C., Sakagami H., Saglamtas R., SERT Y., et al.
Polycyclic Aromatic Compounds
, cilt.45, sa.9, ss.1759-1790, 2025 (SCI-Expanded, Scopus)
2025
20255. Tumor-specific cytotoxicity of pyrazole-based chalcone derivatives in human oral squamous cell carcinoma cell lines
Tuğrak Sakarya M., GÜL H. İ., Sakagami H., Nagai J., Uesawa Y., Bandow K.
Turkish Journal of Biology
, cilt.49, sa.6, ss.712-727, 2025 (SCI-Expanded, Scopus, TRDizin)
2024
20246. In Vitro Enzyme Activity and Molecular Docking Studies of Pyrazoline Derivatives as Monoamine Oxidase Inhibitors
Sakarya M. T., GÜL H. İ., YAMALI C., ÖZKAY Y., Tok T. T.
Pharmaceutical Chemistry Journal
, cilt.58, sa.3, ss.419-427, 2024 (SCI-Expanded, Scopus)
2023
20237. Current Pharmaceutical Research on the Significant Pharmacophore Mannich bases in Drug Design
Yamalı C., Gül M., Gül H. I.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
, cilt.23, sa.27, ss.2590-2608, 2023 (SCI-Expanded, Scopus)
2023
20238. Obesity and Obesity-Related Diseases and Treatments
Aydın A. S., Sivri T. R., Gül H. İ.
Pharmata
, cilt.3, sa.2, ss.64-70, 2023 (Hakemli Dergi)
2023
20239. Higher number of microplastics in tumoral colon tissues from patients with colorectal adenocarcinoma
Çetin M., Demirkaya Miloğlu F., Kılıç Baygutalp N., Ceylan O., Yıldırım S., Eser G., et al.
ENVIRONMENTAL CHEMISTRY LETTERS
, cilt.21, sa.2, ss.639-646, 2023 (SCI-Expanded, Scopus)
2022
202210. Chemical Structure and Synthesis of Baloxavir Marboxil, A Novel Endonuclease Inhibitor For The Treatment Influenza : An Overview
AYDIN A. S., GÜL H. İ.
International Journal of PharmATA , cilt.2, sa.3, ss.20-27, 2022 (Hakemli Dergi)
2022
202211. In Vitro and In Silico Cytotoxicity Evaluation of Some Isatin Mannich Bases on Human Melanoma Cells
Işgör M. M., Küçükgül A., Karaman M., Özmen Özgün D., Yanık T., Gül H. I., et al.
Journal of Applied Biological Sciences (JABS)
, cilt.16, sa.1, ss.102-114, 2022 (Hakemli Dergi)
2021
202112. Effects of a Novel Benzenesulfonamide 4-(3-(4-Bromophenyl)-5-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl) on Antioxidant Enzymes and Hematological Parameters of Rainbow Trout (Oncorhynchus mykiss)
Ozgun D. O., Alak G., Uçar A., Bilginer S., Gül H. I., Kocaman M., et al.
PAKISTAN JOURNAL OF ZOOLOGY
, cilt.53, sa.6, ss.2083-2089, 2021 (SCI-Expanded, Scopus)
2021
202113. Monoamine Oxidase (MAO) as a Potential Target for Anticancer Drug Design and Development.
Aljanabi R., Alsous L., Sabbah D. A., Gul H. İ., Gul M., Bardaweel S. K.
Molecules (Basel, Switzerland)
, cilt.26, sa.19, 2021 (SCI-Expanded, Scopus)
2021
202114. Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides
YAMALI C., Sakagami H., Uesawa Y., Kurosaki K., Satoh K., Masuda Y., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.217, 2021 (SCI-Expanded, Scopus)
2021
202115. Synthesis and in vitro carbonic anhydrases and acetylcholinesterase inhibitory activities of novel imidazolinone-based benzenesulfonamides
TUĞRAK M., GÜL H. İ., Demir Y., LEVENT S., GÜLÇİN İ.
ARCHIV DER PHARMAZIE
, cilt.354, sa.4, 2021 (SCI-Expanded, Scopus)
2021
202116. Effects of a Novel Benzenesulfonamide 4-(3-(4-Bromophenyl)-5-(2,4-dimethoxyphenyl)- 4,5-dihydro-1H-pyrazol-1-yl) on Antioxidant Enzymes and Hematological Parameters of Rainbow Trout (Oncorhynchus mykiss)
Özmen Özgün D., Alak G., Uçar A., Bilginer S., Gül H. I., Kocaman E. M., et al.
PAKISTAN JOURNAL OF ZOOLOGY
, cilt.53, sa.6, ss.2083-2089, 2021 (Scopus)
2021
202117. New Chalcone Derivatives with Pyrazole and Sulfonamide Pharmacophores as Carbonic Anhydrase Inhibitors
TUĞRAK M., GÜL H. İ., Akincioglu H., GÜLÇİN İ.
LETTERS IN DRUG DESIGN & DISCOVERY
, cilt.18, sa.2, ss.191-198, 2021 (SCI-Expanded, Scopus)
2021
202118. Synthesis and biological evaluation of new pyrazolebenzene-sulphonamides as potential anticancer agents and hCA I and II inhibitors
TUĞRAK M., GÜL H. İ., Sakagami H., Kaya R., GÜLÇİN İ.
TURKISH JOURNAL OF CHEMISTRY
, cilt.45, sa.3, ss.528-562, 2021 (SCI-Expanded, Scopus, TRDizin)
2021
202119. Biological activities of a newly synthesized pyrazoline derivative 4-(3-(4-bromophenyl)-5-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamide (B4) compound on rainbow trout alevins, Oncorhynchus mykiss
Uçar A., Ozgun D. O., Alak G., Gül H. I., Kocaman E. M., Parlak V., et al.
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
, cilt.57, sa.1, ss.17-20, 2021 (SCI-Expanded, Scopus)
2021
202120. Phenothiazine-based chalcones as potential dual-target inhibitors toward cholinesterases (AChE, BuChE) and monoamine oxidases (MAO-A, MAO-B)
YAMALI C., Engin F. S., BİLGİNER S., TUĞRAK M., Ozmen Ozgun D., ÖZLİ G., et al.
JOURNAL OF HETEROCYCLIC CHEMISTRY
, cilt.58, sa.1, ss.161-171, 2021 (SCI-Expanded, Scopus)
2021
202121. Docking Studies and Antiproliferative Activities of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolone Derivatives as Novel Inhibitors of Phosphatidylinositol 3-Kinase (PI3K alpha)
BİLGİNER S., Bardaweel S. K., Sabbah D. A., GÜL H. İ.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
, cilt.21, sa.6, ss.716-724, 2021 (SCI-Expanded, Scopus)
2020
202022. Inhibitory effects of the chalcones towards carbonic anhydrase I, II and acetylcholinesterase enzymes
TUĞRAK M., YAMALI C., GÜL H. İ., DEMİR Y.
Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi , cilt.13, sa.3, ss.1138-1146, 2020 (TRDizin)
2020
202023. Evaluation of Cytotoxic Properties of N,N'-bis[(1-aryl-3-heteroaryl)propylidene]-hydrazine dihydrochlorides
Küçükoğlu K., Gül H. İ., Sakagami H.
PHARMACEUTICAL CHEMISTRY JOURNAL , cilt.54, sa.8, ss.784-787, 2020 (SCI-Expanded, Scopus)
2020
202024. An experimental work on radiation protection features of some bioactive compounds of Mannich bases
YILMAZ D., KAVAZ E., GÜL H. İ.
Radiation Physics and Chemistry
, cilt.176, 2020 (SCI-Expanded, Scopus)
2020
202025. Synthesis, cytotoxic, and carbonic anhydrase inhibitory effects of new 2-(3-(4-methoxyphenyl)-5-(aryl)-4,5-dihydro-1H-pyrazol-1-yl)benzo[d]thiazole derivatives
TUĞRAK M., GÜL H. İ., Sakagami H., GÜLÇİN İ.
Journal of Heterocyclic Chemistry
, cilt.57, sa.7, ss.2762-2768, 2020 (SCI-Expanded, Scopus)
2020
202026. Deciphering binding mechanism between bovine serum albumin and new pyrazoline compound K4.
Bozkurt E., Gül H. İ.
Luminescence : the journal of biological and chemical luminescence
, cilt.35, ss.534-541, 2020 (SCI-Expanded, Scopus)
2020
202027. New halogenated chalcones with cytotoxic and carbonic anhydrase inhibitory properties: 6-(3-Halogenated phenyl-2-propen-1-oyl)-2(3H)-benzoxazolones
BİLGİNER S., GÜL H. İ., Erdal F. S., Sakagami H., GÜLÇİN İ.
Archiv der Pharmazie
, cilt.353, sa.6, 2020 (SCI-Expanded, Scopus)
2020
202028. Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes
YAMALI C., GÜL H. İ., KAZAZ C., Levent S., GÜLÇİN İ.
Bioorganic Chemistry
, cilt.96, 2020 (SCI-Expanded, Scopus)
2020
202029. Selective fluorometric “Turn-off” sensing for Hg2+ with pyrazoline compound and its application in real water sample analysis
BOZKURT E., GÜL H. İ.
Inorganica Chimica Acta
, cilt.502, 2020 (SCI-Expanded, Scopus)
2020
202030. Synthesis and pharmacological effects of novel benzenesulfonamides carrying benzamide moiety as carbonic anhydrase and acetylcholinesterase inhibitors
Tuğrak M., Gül H. İ., Anıl B., Gülçin İ.
TURKISH JOURNAL OF CHEMISTRY
, cilt.44, sa.6, ss.1601-1628, 2020 (SCI-Expanded, Scopus, TRDizin)
2020
202031. Determination and comparison of the urinary iodine levels of premature infants with and without retinopathy of prematurity
Çinici E., Gülaboğlu M., Çetin M., Kahveci H., Duysak L., Kutlu Z., et al.
TRACE ELEMENTS AND ELECTROLYTES
, cilt.37, sa.4, ss.194-199, 2020 (SCI-Expanded)
2020
202032. Design Synthesis and Biological Activities of Chalcones with Piperonal Moiety,” Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi
TUĞRAK M., GÜL H. İ., ANIL B., AKINCIOĞLU H.
Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi , cilt.13, sa.2, ss.620-630, 2020 (TRDizin)
2020
202033. Synthesis and bioactivities of 1-(4-hydroxyphenyl)-2-((heteroaryl)thio)ethanones as carbonic anhydrase I, II and acetylcholinesterase inhibitors
Yamali C., GÜL H. İ., Demir Y., KAZAZ C., GÜLÇİN İ.
TURKISH JOURNAL OF CHEMISTRY
, cilt.44, sa.4, ss.1058-1067, 2020 (SCI-Expanded, Scopus, TRDizin)
2020
202034. Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties
Bilginer S., Gonder B., Gül H. İ., Kaya R., Gülçin İ., Anıl B., et al.
Journal of Enzyme Inhibition and Medicinal Chemistry
, cilt.35, sa.1, ss.325-329, 2020 (SCI-Expanded, Scopus)
2020
202035. Design, Synthesis and Biological Activities of Chalcones with Piperonal Moiety
TUĞRAK M., GÜL H. İ., ANIL B., AKINCIOĞLU H.
Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi , 2020 (TRDizin)
2020
202036. Acetylcholinesterase inhibitory potency of new pyrazoline derivative
TUĞRAK M., GÜL H. İ., GÜLÇİN İ.
JOURNAL OF RESEARCH IN PHARMACY
, cilt.24, sa.4, ss.464-471, 2020 (ESCI, Scopus, TRDizin)
2020
202037. Acetylcholinesterase inhibitory potency of new pyrazoline derivative,” Journal of research in pharmacy (online), vol. 24, no. 4, pp. 464–471, 2020.
TUĞRAK M., GÜL H. İ., GÜLÇİN İ.
JOURNAL OF RESEARCH IN PHARMACY , cilt.24, sa.4, ss.464-471, 2020 (ESCI, TRDizin)
2020
202038. Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors
Yamali C., GÜL H. İ., Çakır T., Demir Y., GÜLÇİN İ.
LETTERS IN DRUG DESIGN & DISCOVERY
, cilt.17, sa.10, ss.1283-1292, 2020 (SCI-Expanded, Scopus)
2019
201939. Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(<i>3H</i>)-benzoxazolones.
Bilginer S., Gul H. İ., Erdal F., Sakagamı H., Levent S., Gulcin I., et al.
Journal of enzyme inhibition and medicinal chemistry
, cilt.34, ss.1722-1729, 2019 (SCI-Expanded, Scopus)
2019
201940. Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors
YAMALI C., GÜL H. İ., Ece A., BUA S., ANGELİ A., SAKAGAMI H., et al.
BIOORGANIC CHEMISTRY
, cilt.92, 2019 (SCI-Expanded, Scopus)
2019
201941. Fluorescence quenching of novel pyrazoline derivative with aniline in different solvents
BOZKURT E., GÜL H. İ.
Journal of Photochemistry and Photobiology A: Chemistry
, cilt.383, 2019 (SCI-Expanded, Scopus)
2019
201942. New phenolic Mannich bases with piperazines and their bioactivities
GÜL H. İ., TUĞRAK M., GÜL M., MAZLUMOĞLU S., Sakagami H., GÜLÇİN İ., et al.
BIOORGANIC CHEMISTRY
, cilt.90, 2019 (SCI-Expanded, Scopus)
2019
201943. Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors
TUĞRAK M., GÜL H. İ., BANDOW K., Sakagami H., GÜLÇİN İ., Ozkay Y., et al.
BIOORGANIC CHEMISTRY
, cilt.90, 2019 (SCI-Expanded, Scopus)
2019
201944. Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes
Kucukoglu K., GÜL H. İ., TASLIMI P., GÜLÇİN İ., Supuran C. T.
BIOORGANIC CHEMISTRY
, cilt.86, ss.316-321, 2019 (SCI-Expanded, Scopus)
2019
201945. Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity
Ozgun D. O., GÜL H. İ., YAMALI C., Sakagami H., GÜLÇİN İ., Sukuroglu M., et al.
BIOORGANIC CHEMISTRY
, cilt.84, ss.511-517, 2019 (SCI-Expanded, Scopus)
2018
201846. Pyrazoline derived new "off-on-off" fluorescent pH sensors
BOZKURT E., GÜL H. İ., Ozgun D. O.
OPTICAL MATERIALS
, cilt.84, ss.550-555, 2018 (SCI-Expanded, Scopus)
2018
201847. Curcumin analogue 1,5-bis(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)phenyl)penta-1,4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and PKC-theta signaling pathways in human breast carcinoma cells.
Badr G., GUL H. İ., YAMALI C., MOHAMED A., BADR B., Gul M., et al.
Bioorganic chemistry
, cilt.78, ss.46-57, 2018 (SCI-Expanded, Scopus)
2018
201848. Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes.
GUL H. İ., YAMALI C., BULBULLER M., KIRMIZIBAYRAK P., Gul M., ANGELI A., et al.
Bioorganic chemistry
, cilt.78, ss.290-297, 2018 (SCI-Expanded, Scopus)
2018
201849. Crystal structure and theoretical study of (2E)-1-[4-hydroxy-3-(morpholin-4-ylmethyl)-phenyl]-3-(thiophen-2-yl)prop-2-en-1-one
YEŞİLYURT F., Aydin A., GÜL H. İ., AKKURT M., OZCELİK N. D.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, cilt.74, ss.960-968, 2018 (ESCI, Scopus)
2018
201850. New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors
GÜL H. İ., YAMALI C., Sakagami H., ANGELİ A., LEİTANS J., KAZAKS A., et al.
BIOORGANIC CHEMISTRY
, cilt.77, ss.411-419, 2018 (SCI-Expanded, Scopus)
2018
201851. Synthesis, molecular modeling, and biological evaluation of 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes
YAMALI C., GÜL H. İ., Ece A., TASLIMI P., GÜLÇİN İ.
CHEMICAL BIOLOGY & DRUG DESIGN
, cilt.91, sa.4, ss.854-866, 2018 (SCI-Expanded, Scopus)
2018
201852. A novel pyrazoline-based fluorometric "turn-off" sensing for Hg2+
BOZKURT E., GÜL H. İ.
SENSORS AND ACTUATORS B-CHEMICAL
, cilt.255, ss.814-825, 2018 (SCI-Expanded, Scopus)
2018
201853. Cytotoxicity, apoptosis, and QSAR studies of phenothiazine derivedmethoxylated chalcones as anticancer drug candidates
GÜL H. İ., YAMALI C., GÜNEÇAÇAR G., Sakagami H., OKUDAIRA N., UESAWA Y., et al.
Medicinal Chemistry Research , cilt.27, ss.2366-2378, 2018 (SCI-Expanded, Scopus)
2018
201854. Solvent and substituent effect on the photophysical properties ofpyrazoline derivatives: A spectroscopic study
BOZKURT E., GÜL H. İ., METE E.
Journal Of Photochemistry And Photobiology A-Chemistry , cilt.352, ss.35-42, 2018 (SCI-Expanded, Scopus)
2018
201855. Cytotoxicities of novel hydrazone compounds with pyrrolidinemoiety: inhibition of mitochondrial respiration may be a possible mechanism of action for the cytotoxicity of new hydrazones
Küçükoğlu K., Gül H. İ., Gül M., Çetin Atalay R., Geny B.
Medicinal Chemistry Research , cilt.27, ss.2116-2124, 2018 (SCI-Expanded, Scopus)
2018
201856. Synthesis and Cytotoxicities of New Azafluorenones with Apoptotic Mechanism of Action and Cell Cycle Analysis
GÜL H. İ., TUĞRAK M., GÜL M., SAKAGAMİ H., UMEMURA N., ANIL B.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
, cilt.18, sa.12, ss.1770-1778, 2018 (SCI-Expanded, Scopus)
2017
201757. Microwave-assisted synthesis and bioevaluation of new sulfonamides.
GUL H. İ., YAMALI C., YESILYURT F., SAKAGAMI H., KUCUKOGLU K., GÜLÇIN İ., et al.
Journal of enzyme inhibition and medicinal chemistry
, cilt.32, ss.369-374, 2017 (SCI-Expanded, Scopus)
2017
201758. Synthesis, molecular modeling, and biological evaluation of 4-?[5-?aryl-?3-?(thiophen-?2-?yl)?-?4,?5-?dihydro-?1H-?pyrazol-?1-?yl]?benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes
YAMALI C., GÜL H. İ., Ece A., TASLIMI P., GULCIN I.
CHEMICAL BIOLOGY & DRUG DESIGN , cilt.1, sa.1, ss.1, 2017 (SCI-Expanded, Scopus)
2017
201759. Synthesis and structure elucidation of 1-(2,5/3,5-difluorophenyl)-3-(2,3/2,4/2,5/3,4-dimethoxyphenyl)-2-propen-1-ones as anticancer agents
YAMALI C., Ozgun D. O., GÜL H. İ., SAKAGAMI H., KAZAZ C., OKUDAIRA N.
MEDICINAL CHEMISTRY RESEARCH
, cilt.26, sa.9, ss.2015-2023, 2017 (SCI-Expanded, Scopus)
2017
201760. Synthesis and anticancer properties of mono Mannich bases containing vanillin moiety
TUĞRAK M., GÜL H. İ., SAKAGAMI H., METE E.
MEDICINAL CHEMISTRY RESEARCH
, cilt.26, sa.7, ss.1528-1534, 2017 (SCI-Expanded, Scopus)
2017
201761. Investigation of solvent effect on photophysical properties of some sulfonamides derivatives
BOZKURT E., GÜL H. İ., TUĞRAK M.
TURKİSH JOURNAL OF CHEMİSTRY , cilt.41, ss.282-293, 2017 (SCI-Expanded, Scopus, TRDizin)
2017
201762. Synthesis and Cytotoxic Activities of Difluoro-Dimethoxy Chalcones.
YAMALI C., GUL H. İ., OZGUN D., Sakagam H., Umemura N., KAZAZ C., et al.
Anti-cancer agents in medicinal chemistry
, cilt.17, ss.1426-1433, 2017 (SCI-Expanded, Scopus)
2017
201763. Crystal structure of (E)-2-({4-hydroxy-5-methoxy3-[(4-methyl-1-piperazinyl) methyl] phenyl} methylidene)-1-indanone, C23H26N2O3
TUĞRAK M., Aydin A., GÜL H. İ., ŞAHİN E., AKKURT M.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
, cilt.232, sa.1, ss.113-115, 2017 (SCI-Expanded, Scopus)
2017
201764. Energy absorption buildup factors of some potential bioactive compounds in the energy region 0.015-15 MeV
YILMAZ D., GEDIK Z., TUĞRAK M., GÜL H. İ.
SPECTROSCOPY LETTERS
, cilt.50, sa.6, ss.301-306, 2017 (SCI-Expanded, Scopus)
2017
201765. Investigation of solvent effect on photophysical properties of some sulfonamides derivatives
BOZKURT E., GÜL H. İ., TUĞRAK M.
TURKISH JOURNAL OF CHEMISTRY
, cilt.41, sa.2, ss.282-293, 2017 (SCI-Expanded, Scopus, TRDizin)
2017
201766. Synthesis of Mannich Bases by Two Different Methods and Evaluation of their Acetylcholine Esterase and Carbonic Anhydrase Inhibitory Activities
GÜL H. İ., DEMIRTAS A., UCAR G., TASLIMI P., GÜLÇİN İ.
LETTERS IN DRUG DESIGN & DISCOVERY
, cilt.14, sa.5, ss.573-580, 2017 (SCI-Expanded, Scopus)
2017
201767. Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines
GÜL H. İ., METE E., TASLIMI P., GÜLÇİN İ., SUPURAN C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.32, sa.1, ss.189-192, 2017 (SCI-Expanded, Scopus)
2017
201768. Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl] benzenesulfonamides
GÜL H. İ., METE E., EREN S. E., SAKAGAMI H., YAMALI C., SUPURAN C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.32, sa.1, ss.169-175, 2017 (SCI-Expanded, Scopus)
2017
201769. Crystal structure of (E)?-?2-?({4-?hydroxy-?5-?methoxy-?3-?[(4-?methyl-?1-?piperazinyl)?methyl]?phenyl}?methylidene)?-?1-?indanone, C23H26N2O3
TUGRAK M., AYDıN A., GÜL H. İ., Şahin E., AKKURT M.
ZEİTSCHRİFT FUR KRİSTALLOGRAPHİE-NEW CRYSTAL STRUCTURES , cilt.232, ss.113-115, 2017 (SCI-Expanded, Scopus)
2016
201670. Synthesis and carbonic anhydrase inhibitory activities of new thienyl-substituted pyrazoline benzenesulfonamides
METE E., COMEZ B., GÜL H. İ., GÜLÇİN İ., SUPURAN C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, ss.1-5, 2016 (SCI-Expanded, Scopus)
2016
201671. Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1-propanones
UNLUER E., GÜL H. İ., DEMIRTAS A., SAKAGAMI H., UMEMURA N., TANC M., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, ss.105-109, 2016 (SCI-Expanded, Scopus)
2016
201672. Synthesis and Cytotoxic Activity of (4-Substituted-benzylidene)-(3-Phenyl-1,2,4-Oxadiazol-5-YL)Methylamines
KUCUKOGLU K., TUĞRAK M., DEMIRTAS A., SAKAGAMI H., GÜL H. İ.
PHARMACEUTICAL CHEMISTRY JOURNAL
, cilt.50, sa.4, ss.234-238, 2016 (SCI-Expanded, Scopus)
2016
201673. Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymo
GÜL H. İ., YAMALI C., Yaşa A. T., UNLUER E., SAKAGAMI H., TANC M., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, sa.6, ss.1375-1380, 2016 (SCI-Expanded, Scopus)
2016
201674. The Effect of Substituent on Photophysical Properties of Some 4-(2- Substitutedhydrazinyl)Benzenesulfonamides Derivatives
BOZKURT E., GÜL H. İ., Yıldıztekin K. G., Bakkal H.
Journal of Science and Technology , cilt.9, ss.164-171, 2016 (Hakemli Dergi)
2016
201675. Synthesis and Cytotoxic Activity of 4 Substituted benzylidene 3 Phenyl 1 2 4 Oxadiazol 5 yl methylamines
TUĞRAK M., GÜL H. İ.
PHARMACEUTICAL CHEMISTRY JOURNAL , cilt.50, sa.4, ss.234-238, 2016 (SCI-Expanded, Scopus)
2016
201676. Crystal structure of 1-{4-hydroxy-3-[(pyrrolidin-1-yl)methyl]phenyl}-3-phenylprop-2-en-1-one
AYDIN A., AKKURT M., GÜL H. İ., YERDELEN K. Ö., Celik R. C.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, cilt.72, ss.696-703, 2016 (ESCI, Scopus)
2016
201677. Crystal structure of 4-[5-(4-fluorophenyl)-3-(4-hydroxyphenyl)-4,5-dihydropyrazol-1-yl] benzenesulfonamide, C21H18FN3O3S
Aydin A., BİLGİNER S., GÜL H. İ., AKKURT M., METE E.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
, cilt.231, sa.1, ss.81-83, 2016 (SCI-Expanded, Scopus)
2016
201678. Crystal structure of 4-?[5-?(4-?fluorophenyl)?-?3-?(4-?hydroxyphenyl)?-?4,?5-?dihydropyrazol-?1-?yl] benzenesulfonamide, C21H18FN3O3S
AYDıN A., BILGINER S., GÜL H. İ., AKKURT M., METE E.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES , cilt.231, ss.81-83, 2016 (SCI-Expanded, Scopus)
2016
201679. Synthesis of some acrylophenones with N-methylpiperazine and evaluation of their cytotoxicities
GÜL H. İ., TUĞRAK M., Sakagami H.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, sa.1, ss.147-151, 2016 (SCI-Expanded, Scopus)
2016
201680. Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases
YAMALI C., GÜL H. İ., Sakagami H., Supuran C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, ss.125-131, 2016 (SCI-Expanded, Scopus)
2016
201681. Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase
Ozgun D. O., Yamalı C., Gül H. İ., Taslımı P., Gülçin İ., Yanik T., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, sa.6, ss.1498-1501, 2016 (SCI-Expanded, Scopus)
2016
201682. Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol
GÜL H. İ., YAMALI C., Yasa A. T., Unluer E., Sakagami H., Tanc M., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, sa.6, ss.1375-1380, 2016 (SCI-Expanded, Scopus)
2016
201683. Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects
Gül H. İ., Kucukoglu K., Yamalı C., Bilginer S., Yuca H., Ozturk I., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, ss.568-573, 2016 (SCI-Expanded, Scopus)
2016
201684. Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides
GÜL H. İ., TUĞRAK M., Sakagami H., TASLIMI P., GÜLÇİN İ., SUPURAN C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, sa.6, ss.1619-1624, 2016 (SCI-Expanded, Scopus)
2016
201685. Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2,3-dihydroinden-1-one and evaluation of their cytotoxicities
TUĞRAK M., YAMALI C., SAKAGAMI H., GÜL H. İ.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, sa.5, ss.818-823, 2016 (SCI-Expanded, Scopus)
2016
201686. Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration
KUCUKOGLU K., GÜL H. İ., GUL M., Cetin-Atalay R., Baratli Y., Geny B.
Letters in Drug Design & Discovery
, cilt.13, sa.8, ss.734-741, 2016 (SCI-Expanded, Scopus)
2016
201687. Inhibitory effects of benzimidazole containing new phenolic Mannich bases on human carbonic anhydrase isoforms hCA I and II
GÜL H. İ., Yazici Z., Tanc M., Supuran C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, sa.6, ss.1540-1544, 2016 (SCI-Expanded, Scopus)
2016
201688. The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes
YAMALI C., TUĞRAK M., GÜL H. İ., TANC M., SUPURAN C. T.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, sa.6, ss.1678-1681, 2016 (SCI-Expanded, Scopus)
2016
201689. Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines
Kucukoglu K., ORAL F., AYDIN T., YAMALI C., Algul O., Sakagami H., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, ss.20-24, 2016 (SCI-Expanded, Scopus)
2015
201590. Synthesis of 3-aroyl-4-aryl-1-isopropylamino-4-piperidinols and evaluation of the cytotoxicities of the compounds against human hepatoma and breast cancer cell lines
Kucukoglu K., METE E., Cetin-Atalay R., GÜL H. İ.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.30, sa.4, ss.564-568, 2015 (SCI-Expanded, Scopus)
2015
201591. Radiation Parameters of Some Potential Bioactive Compounds
GEDIK Z., TUĞRAK M., DASTAN A., GÜL H. İ., YILMAZ D.
SPECTROSCOPY AND SPECTRAL ANALYSIS
, cilt.35, sa.6, ss.1501-1505, 2015 (SCI-Expanded, Scopus)
2015
201592. Synthesis and biological evaluation of 1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one and its aminomethyl derivatives.
YERDELEN K. Ö., Gul H. İ., SAKAGAMI H., UMEMURA N.
Journal of enzyme inhibition and medicinal chemistry
, cilt.30, ss.383-8, 2015 (SCI-Expanded, Scopus)
2015
201593. Synthesis and Cytotoxicities of 2-[4-hydroxy-(3,5-bis-aminomethyl)-benzylidene]-indan-1-ones
TUĞRAK M., GÜL H. İ., Sakagami H.
LETTERS IN DRUG DESIGN & DISCOVERY
, cilt.12, sa.10, ss.806-812, 2015 (SCI-Expanded, Scopus)
2015
201594. Cerebral Lateralization, Depression and Serum S100B Levels in Patients with Fibromyalgia
BAYGUTALP N. K., Yilmaz N., BAYGUTALP F., ÖZTÜRK N., GÜL H. İ., Polat H., et al.
CLINICAL AND INVESTIGATIVE MEDICINE
, cilt.38, sa.4, 2015 (SCI-Expanded, Scopus)
2015
201595. Synthesis and Cytotoxic Activities of a Curcumin Analogue and Its bis-Mannich Derivatives
Yerdelen K. Ö., GÜL H. İ., Sakagami H., UMEMURA N., Sukuroglu M.
LETTERS IN DRUG DESIGN & DISCOVERY
, cilt.12, sa.8, ss.643-649, 2015 (SCI-Expanded, Scopus)
2014
201496. Carbonic anhydrase inhibitors. Phenols incorporating 2-or 3-pyridyl-ethenylcarbonyl and tertiary amine moieties strongly inhibit Saccharomyces cerevisiae beta-carbonic anhydrase
Bilginer S., Unluer E., Gül H. İ., Mete E., Isık S., Vullo D., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.29, sa.4, ss.495-499, 2014 (SCI-Expanded, Scopus)
2014
201497. Synthesis of new N,N'-bis[1-aryl-3-(piperidine-1-yl)propylidene]hydrazine dihydrochlorides and evaluation of their cytotoxicity against human hepatoma and breast cancer cells.
KUCUKOGLU K., GUL H. İ., CETIN-ATALAY R., BARATLI Y., CHARLES A., SUKUROGLU M., et al.
Journal of enzyme inhibition and medicinal chemistry
, cilt.29, ss.420-6, 2014 (SCI-Expanded, Scopus)
2013
201398. Synthesis and anticholinesterase activity of fumaramide derivatives
YERDELEN K. Ö., GÜL H. İ.
MEDICINAL CHEMISTRY RESEARCH
, cilt.22, sa.10, ss.4920-4929, 2013 (SCI-Expanded, Scopus)
2013
201399. Crystal structure of 3-(thiophen-2-yl-carbonyl)-4-(thiophen-2-yl)-1-isopropyl-4-piperidinol, C17H21NO2S2
Aydin A., AKKURT M., GÜL H. İ., METE E., ŞAHİN E.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
, cilt.228, sa.3, ss.355-356, 2013 (SCI-Expanded, Scopus)
2013
2013100. 1-(3-Aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones: A novel group of tumour-selective cytotoxins
Bilginer S., Gül H. İ., Mete E., Das U., Sakagamı H., Umemura N., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.28, sa.5, ss.974-980, 2013 (SCI-Expanded, Scopus)
2013
2013101. Crystal structure of 3-(p-bromobenzoyl)-4-(p-bromophenyl)-1-isopropyl-4-piperidinol hydrochloride, C21H24Br2ClNO2
Aydin A., AKKURT M., GÜL H. İ., METE E., ŞAHİN E.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
, cilt.228, sa.3, ss.381-382, 2013 (SCI-Expanded, Scopus)
2012
2012102. N-(2-Benzoyl-eth-yl)propan-2-aminium chloride.
AYDıN A., AKKURT M., Gul H. İ., METE E., SAHIN E.
Acta crystallographica. Section E, Structure reports online
, cilt.68, 2012 (SCI-Expanded, Scopus)
2012
2012103. N-[2-(4-Methyl-benzo-yl)eth-yl]propan-2-aminium chloride.
AYDıN A., AKKURT M., Gul H. İ., METE E., SAHIN E.
Acta crystallographica. Section E, Structure reports online
, cilt.68, 2012 (SCI-Expanded, Scopus)
2012
2012104. N-[2-(4-Bromobenzoyl)ethyl]isopropylaminium chloride
Aydin A., AKKURT M., GÜL H. İ., METE E., ŞAHİN E.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, cilt.68, 2012 (SCI-Expanded, ESCI, Scopus)
2011
2011105. 3-(4-Chlorobenzoyl)-4-(4-chlorophenyl)-1-phenethylpiperidin-4-ol
Aydin A., AKKURT M., METE E., ŞAHİN E., GÜL H. İ.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
, cilt.67, 2011 (SCI-Expanded, Scopus)
2011
2011106. Synthesis and Antifungal Evaluation of 1-Aryl-2-dimethylaminomethyl-2-propen-1-one Hydrochlorides
Mete E., Gül H. İ., Bilginer S., Algul O., Topaloglu M. E., Güllüce M., et al.
MOLECULES
, cilt.16, sa.6, ss.4660-4671, 2011 (SCI-Expanded, Scopus)
2011
2011107. The Design and Cytotoxic Evaluation of Some 1-Aryl-3-isopropylamino-1-propanone Hydrochlorides towards Human Huh-7 Hepatoma Cells
METE E., GÜL H. İ., Cetin-Atalay R., Das U., ŞAHİN E., GÜL M., et al.
ARCHIV DER PHARMAZIE
, cilt.344, sa.5, ss.333-339, 2011 (SCI-Expanded, Scopus)
2011
2011108. Synthesis of some Mannich bases with dimethylamine and their hydrazones and evaluation of their cytotoxicity against Jurkat cells
Kucukoglu K., GÜL M., ATALAY M., METE E., KAZAZ C., HANNINEN O., et al.
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
, cilt.61, sa.6, ss.366-371, 2011 (SCI-Expanded, Scopus)
2010
2010109. Biological Activity of 1-Aryl-3-phenethylamino-1-propanone Hydrochlorides and 3-Aroyl-4-aryl-1-phenethyl-4-piperidinols on PC-3 Cells and DNA Topoisomerase I Enzyme
METE E., GÜL H. İ., Canturk P., TOPÇU Z., Pandit B., GÜL M., et al.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
, cilt.65, ss.647-652, 2010 (SCI-Expanded, Scopus)
2010
2010110. The effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinolhydrochloride (C1), indomethacin, nimesulide and rofecoxib on cyclooxygenase activities in carrageenan-induced paw edema model
ŞAHİN Y. N., Demircan B., SÜLEYMAN H., AKSOY H., GÜL H. İ.
TURKISH JOURNAL OF MEDICAL SCIENCES
, cilt.40, sa.5, ss.723-728, 2010 (SCI-Expanded, Scopus, TRDizin)
2010
2010111. Structural analysis of 1 aryl 3 isopropylamino 1 propanone hydrochlorides
ANIL B., ŞAHİN E., METE E., GÜL H. İ.
ACTA CRYSTALLOGRAPHICA SECTION A , cilt.66, ss.131, 2010 (SCI-Expanded)
2010
2010112. Synthesis and Antifungal Activity of 1-Aryl-3-phenethylamino-1-propanone Hydrochlorides and 3-Aroyl-4-aryl-1-phenethyl-4-piperidinols
METE E., OZELGUL C., KAZAZ C., Yurdakul D., Sahin F., GÜL H. İ.
ARCHIV DER PHARMAZIE
, cilt.343, sa.5, ss.291-300, 2010 (SCI-Expanded, Scopus)
2010
2010113. Cytotoxic 2-benzylidene-6-(nitrobenzylidene)cyclohexanones which display substantially greater toxicity for neoplasms than non-malignant cells
Das U., Doroudi A., Gul H. İ., Pati H. N., KAWASE M., Sakagami H., et al.
BIOORGANIC & MEDICINAL CHEMISTRY
, cilt.18, sa.6, ss.2219-2224, 2010 (SCI-Expanded, Scopus)
2010
2010114. The effects of compound of C1 indomethacin nimesulide and rofecoxib on COX and NO in vivo and in vitro
GÜL H. İ., DEMİRCAN B., ŞAHİN Y. N., SÜLEYMAN H., AKSOY H.
Febs Journal , cilt.273, ss.289, 2010 (SCI-Expanded, Scopus)
2010
2010115. Structural Analysis of 1-aryl-3-isopropilamino-1-propanone hydrochlorides
ANIL B., ŞAHİN E., METE E., GÜL H. İ.
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES
, cilt.66, 2010 (SCI-Expanded)
2009
2009116. Evaluation of the anti-inflammatory activity of N,N '-bis(3-dimethylamino-1-phenyl-propylidene) hydrazine dihydrochloride
GÜL H. İ., Suleyman H., GÜL M.
PHARMACEUTICAL BIOLOGY
, cilt.47, sa.10, ss.968-972, 2009 (SCI-Expanded, Scopus)
2009
2009117. Cytotoxic activity of 4'-hydroxychalcone derivatives against Jurkat cells and their effects on mammalian DNA topoisomerase I.
GUL H. İ., CIZMECIOGLU M., ZENCIR S., Gul M., CANTURK P., ATALAY M., et al.
Journal of enzyme inhibition and medicinal chemistry
, cilt.24, ss.804-7, 2009 (SCI-Expanded, Scopus)
2009
2009118. Cytotoxicity of 1-Aryl-3-buthylamino-1-propanone Hydrochlorides against Jurkat and L6 Cells
GÜL M., METE E., ATALAY M., ARIK M., GÜL H. İ.
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH
, cilt.59, sa.7, ss.364-369, 2009 (SCI-Expanded, Scopus)
2009
2009119. AIDS and drugs in AIDS treatment
SULUKAN E. E., KÜÇÜKOĞLU K., GÜL H. İ.
Ankara Universitesi Eczacilik Fakultesi Dergisi
, 2009 (Scopus)
2008
2008120. Synthesis and cytotoxicity of novel 3-aryl-1-(3'-dibenzylaminomethyl-4'-hydroxyphenyl)-propenones and related compounds.
GUL H. İ., YERDELEN K. Ö., DAS U., Gul M., PANDIT B., LI P., et al.
Chemical & pharmaceutical bulletin
, cilt.56, ss.1675-81, 2008 (SCI-Expanded, Scopus)
2008
2008121. Effect of some bis Mannich bases and corresponding piperidinols on DNA topoisomerase I.
CANTURK P., KUCUKOGLU K., TOPCU Z., Gul M., GUL H. İ.
Arzneimittel-Forschung
, cilt.58, ss.686-91, 2008 (SCI-Expanded, Scopus)
2007
2007122. Synthesis of 1-aryl-3-phenethylamino-1-propanone hydrochlorides as possible potent cytotoxic agents
METE E., GÜL H. İ., KAZAZ C.
MOLECULES
, cilt.12, sa.12, ss.2579-2588, 2007 (SCI-Expanded, Scopus)
2007
2007123. Synthesis of 4 '-hydroxy-3 '-piperidinomethylchalcone derivatives and their cytotoxicity against PC-3 cell lines
Gul H. İ., YERDELEN K. O., Gul M., DAS U., PANDIT B., LI P., et al.
ARCHIV DER PHARMAZIE
, cilt.340, sa.4, ss.195-201, 2007 (SCI-Expanded, Scopus)
2007
2007124. Evaluation of anticonvulsant activities of bis(3-aryl-3-oxo-propyl) ethylamine hydrochlorides and 4-aryl-3-arylcarbonyl-1-ethyl-4-piperidinol hydrochlorides.
Gul H. İ., CALLS U., OZTURK Z., TUTAR E., CALIKIRAN L.
Arzneimittel-Forschung
, cilt.57, ss.133-6, 2007 (SCI-Expanded, Scopus)
2007
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SULEYMAN H., GUL H. İ., Gul M., ALKAN M., GOCER F.
Biological & pharmaceutical bulletin
, cilt.30, ss.63-7, 2007 (SCI-Expanded, Scopus)
2006
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DAS U., Gul H. İ., ALCORN J., SHRIVASTAV A., GEORGE T., SHARMA R., et al.
European journal of medicinal chemistry
, cilt.41, ss.577-85, 2006 (SCI-Expanded, Scopus)
2006
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Gul H. İ., DAS U., PANDIT B., LI P.
Arzneimittel-Forschung
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2005
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Gul M., ATALAY M., GUL H. İ., NAKAO C., LAPPALAINEN J., HÄNNINEN O.
Toxicology in vitro : an international journal published in association with BIBRA
, cilt.19, ss.573-80, 2005 (SCI-Expanded, Scopus)
2005
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GUL H. İ., SAHIN F., Gul M., OZTURK S., YERDELEN K. Ö.
Archiv der Pharmazie
, cilt.338, ss.335-8, 2005 (SCI-Expanded, Scopus)
2005
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DIMMOCK J., DAS U., Gul H. İ., KAWASE M., SAKAGAMI H., BARÁTH Z., et al.
Bioorganic & medicinal chemistry letters
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2005
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Gul M., GUL H. İ., DAS U., HANNINEN O.
Arzneimittel-Forschung
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2004
2004132. Synthesis of some mono-Mannich bases and corresponding azine derivatives and evaluation of their anticonvulsant activity.
Gul H. İ., CALIS U., VEPSALAINEN J.
Arzneimittel-Forschung
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2003
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SULEYMAN H., Gul H. İ., ASOGLU M.
Pharmacological research
, cilt.47, ss.471-5, 2003 (SCI-Expanded, Scopus)
2003
2003134. Cytotoxicity of some azines of acetophenone derived mono-Mannich bases against Jurkat cells.
GUL H. İ., Gul M., VEPSÄLAINEN J., ERCIYAS E., HÄNNINEN O.
Biological & pharmaceutical bulletin
, cilt.26, ss.631-7, 2003 (SCI-Expanded, Scopus)
2003
2003135. Toxicity of some bis Mannich bases and corresponding piperidinols in the brine shrimp (Artemia salina) bioassay.
GUL H. İ., Gul M., ERCIYAS E.
Journal of applied toxicology : JAT
, cilt.23, ss.53-7, 2003 (SCI-Expanded, Scopus)
2002
2002136. Antifungal evaluation of bis Mannich bases derived from acetophenones and their corresponding piperidinols and stability studies.
Gul H. İ., OJANEN T., HÄNNINEN O.
Biological & pharmaceutical bulletin
, cilt.25, ss.1307-10, 2002 (SCI-Expanded, Scopus)
2002
2002137. Effects of Mannich bases on cellular glutathione and related enzymes of Jurkat cells in culture conditions.
Gul M., GUL H. İ., HÄNNINEN O.
Toxicology in vitro : an international journal published in association with BIBRA
, cilt.16, ss.107-12, 2002 (SCI-Expanded, Scopus)
2002
2002138. Antimicrobial evaluation of some Mannich bases of acetophenones and representative quaternary derivatives.
Gul H. İ., DENIZCI A., ERCIYAS E.
Arzneimittel-Forschung
, cilt.52, ss.773-7, 2002 (SCI-Expanded, Scopus)
2002
2002139. Cytotoxic activities of some mono and bis Mannich bases derived from acetophenone in brine shrimp bioassay.
GUL H. İ., Gul M., HÄNNINEN O.
Arzneimittel-Forschung
, cilt.52, ss.840-3, 2002 (SCI-Expanded, Scopus)
2002
2002140. Syntheses and stability studies of some Mannich bases of acetophenones and evaluation of their cytotoxicity against Jurkat cells.
GUL H. İ., Gul M., ERCIYAS E.
Arzneimittel-Forschung
, cilt.52, ss.628-35, 2002 (SCI-Expanded, Scopus)
2002
2002141. Synthesis and evaluation of anticonvulsant activities of some bis Mannich bases and corresponding piperidinols.
Gul H. İ., CALIS U., VEPSALAINEN J.
Arzneimittel-Forschung
, cilt.52, ss.863-9, 2002 (SCI-Expanded, Scopus)
2001
2001142. Antifungal activity of some mono, bis and quaternary Mannich bases derived from acetophenone.
GUL H. İ., OJANEN T., VEPSALAINEN J., Gul M., ERCIYAS E., HANNINEN O.
Arzneimittel-Forschung
, cilt.51, ss.72-5, 2001 (SCI-Expanded, Scopus)
2001
2001143. Effect of acetophenone derived Mannich bases on cellular glutathione level in Jurkat cells. A possible mechanism of action.
Gul M., GUL H. İ., VEPSALAINEN J., ERCIYAS E., HANNINEN O.
Arzneimittel-Forschung
, cilt.51, ss.679-82, 2001 (SCI-Expanded, Scopus)
2000
2000144. Cytotoxic activities of mono and bis Mannich bases derived from acetophenone against Renca and Jurkat cells.
GUL H. İ., VEPSALAINEN J., Gul M., ERCIYAS E., HANNINEN O.
Pharmaceutica acta Helvetiae
, cilt.74, ss.393-8, 2000 (Hakemli Dergi)
1994
1994145. Antimicrobial evaluation of some styryl ketone derivatives and related thiol adducts.
ERCIYAS E., Erkaleli H. İ., COSAR G.
Journal of pharmaceutical sciences
, cilt.83, ss.545-8, 1994 (SCI-Expanded, Scopus)
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International IVEK BIO Congress, İstanbul, Türkiye, 26 - 28 Kasım 2018, (Tam Metin Bildiri)
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International The International Congress of Eurasian Natural Nutrition and Healthy Life’2018, 12 - 14 Temmuz 2018, (Özet Bildiri)
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3rd INTERNATIONAL CONFERENCE ONADVANCES INNATURAL APPLIED SCIENCEICANAS 2018, Antalya, Türkiye, 9 - 12 Mayıs 2018, (Özet Bildiri)
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3rd International Conference on Advances in Natural and Applied Sciences (ICANAS 2018), 9 - 12 Mayıs 2018, (Özet Bildiri)
2018
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2018
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2017
201742. Synthesis of Chalcone Derivatives as Selective MAO-B Inhibitors
Günaşaçar G., OZGUN D. O., GÜL H. İ., sağlık B. N., Özkay Y.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201743. DISCOVERY OF NOVEL INDENO-PYRIDINE DERIVATIVES AS ANTICANCER
GÜL H. İ., TUĞRAK M., Sakagami H.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201744. Synthesis of Novel Pyrazolines and Their Inhibitory Effects on hCA IX and XII Isoenzymes
GÜL H. İ., YAMALI C., SUPURAN C.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201745. Synthesis of 4-(2-(5,6-dimethoxy-1H-inden-1-ylidene)hydrazineyl)benzenesulfonamide and Its Structural Elucidation by NMRs
Koca M., GÜL H. İ.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201746. Bioactivities of Isatin Mannich Bases
OZGUN D. O., GÜL H. İ., YAMALI C.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201747. Design, Synthesis and Bioevaluation of Pyrazoline Derivatives Bearing Primary Sulfonamide As Carbonic Anhydrase Inhibitors
GÜL H. İ., YAMALI C., ÖZMEN ÖZGÜN D., GÜLÇİN İ.
3 rd International Multidisciplinary Symposium on Drug Research and Development - DRD 2017 , Erzurum, Turkey, 5 - 07 Ekim 2017, (Özet Bildiri)
2017
201748. SYNTHESIS OF NEW MANNICH BASES
TUĞRAK M., GÜL H. İ.
International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201749. Synthesis, Molecular Modeling and Biological Evaluation of4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamides
YAMALI C., GÜL H. İ., Ece A., GÜLÇİN İ.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.100, (Tam Metin Bildiri)
2017
201750. SYNTHESIS OF NEW MANNICH BASES
TUĞRAK M., GÜL H. İ., Mazlumoğlu S.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201751. SYNTHESIS AND CARBONIC ANHYDRASE INHIBITORY ACTIVITIES OF SOME NOVEL AZAFLUORENONE DERIVATIVES
GÜL H. İ., TUĞRAK M., GULCIN I.
3 rd International Multidisciplinary Symposium on Drug Research and Development0, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201752. Synthesis of Chalcone Derivatives as Selective MAO-B Inhibitors
Günaşaçar G., OZGUN D. O., GÜL H. İ., sağlık B. N., Özkay Y.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201753. Synthesis of 4-(2-(5,6-dimethoxy-1H-inden-1-ylidene)hydrazineyl)benzenesulfonamide and Its Structural Elucidation by NMRs
Koca M., GÜL H. İ.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201754. CYTOTOXIC ACTIVITIES OF NEW SULPHONAMIDES ON OSCC
TUĞRAK M., GÜL H. İ., Sakagami H.
3 rd International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201755. DISCOVERY OF NOVEL INDENO-PYRIDINE DERIVATIVES AS ANTICANCER AGENTS
TUĞRAK M., GÜL H. İ.
International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Türkiye, 5 - 07 Ekim 2017, ss.1, (Tam Metin Bildiri)
2017
201756. Anti-Kanser Aktivitesi Olan Yeni Pirazolin Türevleri ve Farklı Çözücüler Arasındaki EtkileşimlerinSpektroskopik Tekniklerle İncelenmesi
BOZKURT E., GÜL H. İ., METE E.
29. Ulusal Kimya Kongresi, Ankara, Türkiye, 10 - 14 Eylül 2017, (Özet Bildiri)
2017
201757. Carbonic Anhydrase Isoenzymes inhibition effects of new pyrazoline benzenesulfomamides
ÖZMEN ÖZGÜN D., GÜL H. İ., YAMALI C., GÜLÇİN İ., SUPURAN C. T.
3RD SARELLİTE MEETING ON CARBONIC ANHYDRASE NEW TRENDS IN CARBONIC ANHYDRASES RESEARCH, Florence, İtalya, 24 - 27 Mayıs 2017, (Özet Bildiri)
2017
201758. SYNTHESIS AND CARBONIC ANHYDRASE INHIBITOR ACTIVITY OF MONO MANNICH BASES CONTAINING VANILLIN MOIETY
TUĞRAK M., GÜL H. İ., GÜLÇİN İ., Sakagami H., ÖZMEN ÖZGÜN D.
New Trends in Carbonic Anhydrases Research, Montecatini, İtalya, 24 - 27 Mayıs 2017, (Özet Bildiri)
2017
201759. Carbonic Anhydrase isoenzymes inhibition effects of new pyrazoline benzenesulfonamides
Özgün D. O., GÜL H. İ., YAMALI C., GÜLÇİN İ., Supuran C. T.
The 3rd Satellite Meeting on Carbonic Anhydrase, Montecatini Terme, İtalya, 24 - 27 Mayıs 2017, ss.74, (Tam Metin Bildiri)
2017
201760. SYNTHESIS AND BIOACTIVITIES OF PHENOLIC CHALCONE AND BIS MANNICH BASES
TUĞRAK M., GÜL H. İ., GÜLÇİN İ., Sakagami H., ÖZMEN ÖZGÜN D.
New Trends in Carbonic Anhydrases research, Montecatini, İtalya, 24 - 27 Mayıs 2017, (Özet Bildiri)
2017
201761. SYNTHESIS AND INVESTIGATION OF CARBONIC ANHYDRASE INHIBITOR ACTIVITY OF SOME NOVEL SULPHONAMIDE DERIVATIVES
TUĞRAK M., GÜL H. İ., GÜLÇİN İ., Sakagami H., ÖZMEN ÖZGÜN D.
New Trends in Carbonic Anhydrases Research, Montecatini, İtalya, 24 - 27 Mayıs 2017, (Özet Bildiri)
2017
201762. SYNTHESIS AND EVALUATION OF CYTOTOXICITIES OF NEW PYRAZOLINE BENZENESULFONAMIDES
ÖZMEN ÖZGÜN D., GÜL H. İ.
ICSTSS, DEIRA, 13 - 14 Şubat 2017, (Özet Bildiri)
2017
201763. Role of eugenol in the amelioration of peptic ulcer in indomethacin-induced rats
EKİNCİ AKDEMİR F. N., GÜRSUL C., GÜL H. İ., GÜLÇİN İ.
International Conference on Advances in Natural and Applied Sciences-ICANAS, 18 - 21 Nisan 2017, (Özet Bildiri)
2017
201764. Illumination of Chemical Structures of Some Indeno Pyridine Compounds by 1D and 2D NMR Techniques
TUĞRAK M., ANIL B., GÜL H. İ.
5. Drug Chemistry, Antalya, Türkiye, 30 Mart - 02 Nisan 2017, (Tam Metin Bildiri)
2017
201765. Bazı İndenopiridin Bileşiklerinin Kimyasal Yapılarının 1D ve 2D NMR Teknikleriyle Aydınlatılması
TUĞRAK M., ANIL B., GÜL H. İ.
5.İLAÇ KİMYASI KOGRESİ, Antalya, Türkiye, 30 Mart - 02 Nisan 2017, (Özet Bildiri)
2017
201766. Yeni Sülfonamit Bileşiklerin Antimikrobiyal Aktivitelerinin Değerlendirilmesi
METE E., GÜL H. İ., ADIGÜZEL A.
5. İlaç Kimyası Kongrei, 30 Mart - 02 Nisan 2017, ss.110, (Özet Bildiri)
2017
201767. Bazı İndenopiridin Bileşiklerinin Kimyasal Yapılarının 1D ve 2D NMR ile Aydınlatılması
TUĞRAK M., anıl B., GÜL H. İ.
Uluslararası Katılımlı “5. İlaç Kimyası: İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Antalya, Türkiye, 30 Mart - 02 Nisan 2017, ss.1, (Tam Metin Bildiri)
2017
201768. Bazı Pirazolinlerin Sentezi ve Karbonik Anhidraz I İzoenzimi Üzerindeki İnhibisyon Profili
GÜL H. İ., METE E., TASLIMI P., GÜLÇİN İ., SUPURAN C. T.
5. İlaç Kimyası: İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, 30 Mart - 02 Nisan 2017, (Özet Bildiri)
2017
201769. Bazı İndenopiridin Bileşiklerinin Kimyasal Yapılarının 1D ve 2D NMR ile Aydınlatılması
TUĞRAK M., GÜL H. İ.
Uluslararası Katılımlı “5. İlaç Kimyası: İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Antalya, Türkiye, 30 Mart - 02 Nisan 2017, ss.1, (Tam Metin Bildiri)
2016
201670. Cytotoxic Activities of Indanone Derived Mannich Bases
GÜL H. İ.
International Bahçeşehir University (BAU) Drug Design Congress, 13 - 15 Ekim 2016, (Tam Metin Bildiri)
2016
201671. Synthesis Cytotoxities and Docking Studies of New Chalcones
YAMALI C., GÜL H. İ., ÖZMEN ÖZGÜN D., TUTAR Y.
4th International Bahçeşehir University (BAU) Drug Design Congress, 13 - 15 Ekim 2016, (Özet Bildiri)
2016
201672. The design synthesis and NMR analysis of six compounds of 6 3 aryl 2 propenoyl 2 3H benzoxazolones
BİLGİNER S., Engin F. S., GÜL H. İ.
International Bahçeşehir University (BAU) Drug Design Congress, 13 - 15 Ekim 2016, (Özet Bildiri)
2016
201673. Synthesis and Cytotoxic Activities of Difluoro Dimethoxy Chalcones
ÖZMEN ÖZGÜN D., GÜL H. İ., YAMALI C., Sakagami H.
4th International BAU Drug Design Congress, 13 - 15 Ekim 2016, (Özet Bildiri)
2016
201674. Crystal structure of 4 5 4 fluorophenyl 3 4 hydroxyphenyl 4 5 dihydropyrazol 1 yl benzenesulfonamide C21H18FN3O3S
BİLGİNER S., GÜL H. İ.
4th International Bahçeşehir University (BAU) Drug Design Congress, 13 - 15 Ekim 2016, (Özet Bildiri)
2016
201675. Synthesis and spectral analysis of potentially bioactive chalcones
BİLGİNER S., GÜL H. İ.
International Bahçeşehir University (BAU) Drug Design Congress, 13 - 15 Ekim 2016, (Özet Bildiri)
2016
201676. hCA IX and XII Inhibition Studies of 4-[3-( 4-Hydroxyphenyl) -5-aryl-4,5-dihydro-pyrazol-1-yl]benzenesulfonamides
Mete E., Gül H. İ., Yamalı C., Supuran C.
4th International BAU Drug Design CongressUluslararası Özet bildiri, İstanbul, Türkiye, 13 - 16 Ekim 2016, (Özet Bildiri)
2016
201677. Synthesis and 1H NMR Analysis of Seven Compounds of 2 p substituted benzylidene 2 3 dihydro 1H indan1 ones
GÜNEŞAÇAR G., ÖZMEN ÖZGÜN D., GÜL H. İ.
International Bahçeşehir University (BAU) Drug Design Congress, 13 - 15 Ekim 2016, (Özet Bildiri)
2016
201678. Synthesis and Cytotoxicities of New Sulfonamides
GÜL H. İ., YAMALI C., Sakagami H.
4th International Bahçeşehir University (BAU) Drug Design, 13 - 15 Ekim 2016, (Özet Bildiri)
2016
201679. Synthesis and Evaluation of Cytotoxicities of 4 5 2 4 Dimethoxy phenyl 3 substituedphenyl 4 5 dihydro 1H pyrazol 1 yl Benzenesulfonamide Derivatives
ÖZMEN ÖZGÜN D., GÜL H. İ., Sakagami H.
International Conference on Advances in Natural and Applied Sciences, Antalya, Türkiye, 21 - 23 Nisan 2016, (Özet Bildiri)
2016
201680. Synthesis of 1,3,5 trisubstituted pyrazolines
Mete E., Çömez B., Gül H. İ.
Anatolian Conference on Synthetic Organic Chemistry ACSOC II, Aydın, Türkiye, 21 - 24 Mart 2016, (Özet Bildiri)
2015
201581. Synthesis of new 1 2 4 oxadiazoles
KÜÇÜKOĞLU K., TUĞRAK M., DEMIRTAS A., Sakagami H., GÜL H. İ.
Trans Mediterranean Colloquium on Heterocyclic ChemistryTRAMECH VIII, 11 - 15 Kasım 2015, (Özet Bildiri)
2015
201582. Cytotoxicities of New Piperidinols
METE E., GÜL H. İ., KÜÇÜKOĞLU K.
Trans Mediterranean Colloquium on Heterocyclic Chemistry (TRAMECH), Antalya, Türkiye, 11 - 15 Kasım 2015, (Özet Bildiri)
2015
201583. Synthesis of 4 2 substituted hydrazinyl benzenesulfonamides and their carbonic anhydrase inhibitory effects
GÜL H. İ., KÜÇÜKOĞLU K., YAMALI C., BİLGİNER S., YUCA H., ÖZTÜRK İ., et al.
International Multidisciplinary Symposium on Drug Research and Development, 15 - 17 Ekim 2015, (Özet Bildiri)
2015
201584. NEW ACRYLOPHENONE DERIVATIVES of 1 ARYL 2 NMETHYLPIPERAZINOMETHYL 2 PROPEN 1 ONE SYNTHESIS and CYTOTOXIC ACTIVITY
TUĞRAK M., GÜL H. İ., Sakagami H.
InternationalMultidisciplinary Symposium on Drug Research and Development 2015, 15 - 17 Ekim 2015, (Özet Bildiri)
2015
201585. SYNTHESIS and SPECTRAL ANALYSIS of2 4 HYDROXY 3 5 BIS AMINOMETHYL BENZYLIDENE INDAN 1 ONES
TUĞRAK M., GÜL H. İ., Sakagami H.
International Multidisciplinary Symposium on Drug Research and DevelopmenT, 15 - 17 Ekim 2015, (Özet Bildiri)
2015
201586. Cerebral lateralization depression and serum S100B levels in patıents with fibromyalgia syndrome
KILIÇ BAYGUTALP N., YILMAZ N., BAYGUTALP F., ÖZTÜRK N., GÜL H. İ., POLAT H., et al.
Klinik Biyokimya Uzmanları Derneği Uluslarası Katılımlı Kongre ve LAB-EXPO 2015, Türkiye, 1 - 05 Eylül 2015
2015
201587. Cerebral Lateralization, Depression, and Serum S-100B Levels in Patients with Fibromyalgia Syndrome
KILIÇ BAYGUTALP N., YILMAZ N., BAYGUTALP F., ÖZTÜRK N., GÜL H. İ., POLAT H., et al.
Uluslararası Katılımlı Kongre-LAB EXPO 2015, Elazığ, Türkiye, 1 - 05 Eylül 2015, ss.222, (Özet Bildiri)
2015
201588. Cerebral Lateralization Depression and Serum S100BLevels in Patients with Fibromyalgia
KILIÇ BAYGUTALP N., Yılmaz N., Baygutalp F., ÖZTÜRK N., GÜL H. İ., POLAT H., et al.
Klinik Biyokimya Uzmanları Derneği-Uluslararası Kaytılımlı Kongre-Lab-EXPO2015, Türkiye, 1 - 05 Eylül 2015, (Özet Bildiri)
2015
201589. İndanon dan Türevlenen Çeşitli Bileşikler ve Biyoaktiviteleri
GÜL H. İ.
27. Ulusal Kimya Kongresi, Çanakkale, Türkiye, 23 - 28 Ağustos 2015
2015
201590. 3-Aroil-4-Aril-1-İzopropilamino-4-Piperidinollerin Sentez ve Yapı Aydınlatma Çalışması
Mete E., Gül H. İ., Küçükoğlu K.
27. Ulusal Kimya Kongresi, Çanakkale, Türkiye, 23 - 28 Ağustos 2015, (Özet Bildiri)
2015
201591. DESIGN SYNTHESIS ANDCYTOTOXICITIES OF HALOGEN BEARINGNEW PHENOLIC BIS MANNICH BASES
YAMALI C., GÜL H. İ., Sakagami H.
11th International Symposium of Pharmaceutical Sciences, 9 - 12 Haziran 2015, (Özet Bildiri)
2013
201392. Crystal Structure of 3-(Thiophen-2-yl-carbonyl) -4-(thiophen-2-yl)-1-isopropyl-4-piperidinol, C17H21NO2S2
Mete E., Gül H. İ., Aydın A., Akkurt M., Şahin E.
International Multidisciplinary Symposium On Drug Research Development, Antalya, Türkiye, 28 - 30 Kasım 2013, (Özet Bildiri)
2012
201293. Synthesis of 1-Aryl-2-dimethylaminomethyl-2-propen-1-one Hydrochlorides by Conventional Heating and Microwave Irradiation and Evaluation of Their Antifungal Activities
Mete E., Bilginer S., Algül Ö., Gül H. İ., Topaloğlu M. E., Güllüce M., et al.
26. Ulusal Kimya Kongresi, Muğla, Türkiye, 1 - 06 Ekim 2012, (Özet Bildiri)
2011
201194. X Ray Analysis of a Cytotoxic Piperidinol Compound, 3-(4-Chlorobenzoyl)-4-(4-chlorophenyl)-1-phenetylpiperidin-4-ol
Mete E., Gül H. İ., Aydın A., Akkurt M., Şahin E.
EACR-Anticancer Agents Research Congress, Antalya, Türkiye, 13 - 16 Ekim 2011, (Özet Bildiri)
2011
201195. Synthesis and Antifungal Evaluation of 1-Aryl-2-dimethylaminomethyl-2-propen-1-one Hydrochlorides
Mete E., Bilginer S., Topaloğlu M. E., Güllüce M., Kazaz C., Gül H. İ.
25. Ulusal Kimya Kongresi, Erzurum, Türkiye, 27 Haziran - 02 Temmuz 2011, (Özet Bildiri)
2011
201196. SYNTHESIS OF 1 4 HYDROXY 3 AMINO 1 YL METHYL PHENYL 3 PYRIDINE 3 YL PROPENONES
BİLGİNER S., GÜL H. İ.
INTERNATIONAL DRUG RESEARCH AND DEVELOPMENT, Antalya, Türkiye, 27 - 29 Mayıs 2011, (Özet Bildiri)
2010
201097. Structural Analysis of 1-aryl-3-isopropilamino-1-propanone hydrochlorides
Anıl B., Şahin E., Mete E., Gül H. İ.
26th European Crystallographic Meeting, Darmstadt, Almanya, 29 Ağustos - 02 Eylül 2010, (Özet Bildiri)
2010
201098. The Effect of 1-Aryl-3-Phenethylamino-1-Propanone Hydrochlorides and 3-Aroyl-4-Aryl-1-Phenethyl-4-Piperidinols on DNA Topoisomerase I
Mete E., Gül H. İ., Cantürk P., Topçu Z., Gül M.
IPSMPS 2010 International Postgraduate Student Meeting on Pharmaceutical Sciences, İzmir, Türkiye, 24 - 27 Haziran 2010, (Özet Bildiri)
2010
201099. Cytotoxic Activities of Some Mannich Bases Against PC 3 Cells
METE E., GÜL H. İ., GÜL M., PANDIT B., LI P. K.
IPSMPS 2010 International Postgraduate Student Meeting on Pharmaceutical Sciences, İzmir, Türkiye, 24 - 27 Haziran 2010, (Özet Bildiri)
2010
2010100. Cytotoxicity of 1-Aryl-3-Dimethylamino-1-Propanone Hydrochlorides and Corresponding Azine Derivatives Against Jurkat Cell
GÜL H. İ., GÜL M., Atatlay M., KÜÇÜKOĞLU K., METE E., KAZAZ C.
14th Hellenic Symposium on Medicinal Chemistry, 23 - 25 Nisan 2010, (Özet Bildiri)
2010
2010101. Cytotoxicity of 1-aryl-3-phenethylamino-1-propanone hydrochlorides and 3-aroyl-4-aryl-1-phenethyl-4-piperidinols against PC-3 cells
Mete E., Gül H. İ., Pandıt B., Gül M., Lı P. K.
14th Hellenic Symposium on Medicinal Chemistry (14th HSMC), Thessaloniki, Yunanistan, 23 - 25 Nisan 2010, (Özet Bildiri)
2010
2010102. Cytotoxicity of 1-Aryl-3-dimethylamino-1-propanone Hydrochlorides and Corresponding Azine Derivatives against Jurkat Cells
Gül H. İ., Gül M., Atalay M., Küçükoğlu K., Mete E., Kazaz C.
14th Hellenic Symposium on Medicinal Chemistry (14th HSMC), Thessaloniki, Yunanistan, 23 - 25 Nisan 2010, (Özet Bildiri)
2009
2009103. Cytotoxic activity of 1-arly-3-isoproplyamino-1-propanone Hydrochlorides against huh-7
METE E., GÜL H. İ., ATALAY R., KAZAZ C.
International Symposium on Drug ResearchDevelopment, 4 - 07 Mayıs 2009, (Özet Bildiri)
2009
2009104. Cytotoxic Activity of 1-Aryl-3-Isopropylamino-1-Propanone Hydrochlorides Against HUH-7 Cells
Mete E., Gül H. İ., Kazaz C.
International Symposium on Drug Research and Development “From Chemistry to Medicine" & Educational Fair on "GLP and Laboratory Safety: New Approaches", Ankara, Türkiye, 4 - 07 Mayıs 2009, (Özet Bildiri)
2009
2009105. Cytotoxicity of 1-Aryl-3-Buthylamino-1-Propanone Hydrochlorides against Jurkat Cells
Mete E., Gül H. İ., Gül M., Atalay M., Arık M.
The 1st International Joint Conference on Materials Science & Nanotechnology and Biotecnology-MNB-09-(Future challenges), Cairo, Mısır, 4 - 06 Ocak 2009, (Özet Bildiri)
2007
2007106. Structure Elucidation of mono Mannich base 1-(p-Fluorophenyl)-3-phenethylamino-1-propanone hydrochloride and semicyclic mono Mannich base 3-(p-Fluorobenzoyl)-4-(p-fluorophenyl)- 1-phenethy-4-piperidinol using 1D and 2D NMR Spectroscopy
METE E., KAZAZ C., GÜL H. İ.
ICOC, International Conference on Organic Chemistry, 5 - 09 Haziran 2007, (Özet Bildiri)
2007
2007107. Synthesis of 1-Phenethyl-3-Aroyl-4-Aryl-4-Piperidinols
METE E., GÜL H. İ., KAZAZ C.
International Symposium on Drug Research and Development, 17 - 20 Mayıs 2007, (Özet Bildiri)
2007
2007108. Crystal Structure of 3-(p-ChloroBenzoyl)-4-(p-Chlorophenly)-1-Phenethyl-4-Piperidinol
ŞAHİN E., KAZAZ C., METE E., GÜL H. İ.
International Symposium on Drug Research and Development, 17 - 20 Mayıs 2007, (Özet Bildiri)
2007
2007109. Synthesis of 3-Phenethylamino-1-Phenyl/Substitüed Phenyl-1-PropanoneHydrochlorides
METE E., GÜL H. İ., KAZAZ C.
International Symposium on Drug Research and Development, 17 - 20 Mayıs 2007, (Özet Bildiri)
2007
2007110. Structure Elucidation of Mono Mannich Base 1-(p-Methoxyphenyl)-3-Phenethylamino-1-Propanone Hydrochloride and Semicyclic Mono Mannich Base 3-(p-Methoxybenzoyl)-4-(p-Methoxyphenyl)-1-Phenethy-4-Piperidinol Using 1D and 2D NMR Spectroscopy
Kazaz C., Mete E., Gül H. İ.
International Symposium on Drug Research and Development “From Chemistry to Medicine” DRD 2007, Antalya, Türkiye, 17 - 20 Mayıs 2007, (Özet Bildiri)
2007
2007111. Synthesis of 3-Phenethylamino-1-Phenyl/Substituted Phenyl-1-Propanone Hydrochlorides
Mete E., Gül H. İ., Kazaz C.
International Symposium on Drug Research and Development “From Chemistry to Medicine” DRD 2007, Antalya, Türkiye, 17 - 20 Mayıs 2007, (Özet Bildiri)
2007
2007112. Crystal Structure of 3 p Chlorobenzoyl 4 p Chlorophenyl 1 Phenethyl 4 Piperidinol
ŞAHİN E., KAZAZ C., METE E., GÜL H. İ.
International Symposium on Drug Research and Development “From Chemistry to Medicine” DRD 2007, Antalya, Türkiye, 17 - 20 Mayıs 2007, (Özet Bildiri)
2007
2007113. Evaluation of Cytotoxicity of 1-Aryl-3-Phenethylamino-1-Propanone Hydrochlorides and 1-Phenethyl-3-Benzoyl-4-Aryl-4-Piperidinols By Brine Shrimp Bioassay
Çizmecioğlu M. M., Gül H. İ., Mete E.
International Symposium on Drug Research and Development “From Chemistry to Medicine” DRD 2007, Antalya, Türkiye, 17 - 20 Mayıs 2007, (Özet Bildiri)
2007
2007114. Antifungal Activities of 3-Phenethylamino-1-Aryl-1-Propanone Hydrochlorides and 3-Aroyl-4-Aryl-1-Phenethyl-4-Piperidinols Against Some Plant and Human Pathogenic Fungi
Gül H. İ., Özelgül C., Mete E., Şahin F., Yurdakul D.
International Symposium on Drug Research and Development “From Chemistry to Medicine” DRD 2007, Antalya, Türkiye, 17 - 20 Mayıs 2007, (Özet Bildiri)
2003
2003115. Mannich bazlarının iki değişik deney düzeneğinde Jurkat hücreleri glutatyon düzeylerine etkileri
GÜL M., GÜL H. İ., Vepsalainen J., ERCİYAS E., Hanninen O.
29. Ulusal Fizyoloji Kongresi, Türkiye, 1 - 05 Eylül 2003, (Özet Bildiri)
1999
1999116. Bazı bis Mannich bazlarının 3,3’-etilimino bis(1-aril-1-propanon) hidroklorür, ve onların yapısal izomeri olan piperidinol türevlerinin sitotoksisitelerinin Brine Shrimp bioassay yöntemi ile saptanması
Gül H. İ., Erciyas E., Gül M.
Serbest Radikaller ve Antioksidanlar Araştırma Derneği II. Ulusal Kongresi, Eskişehir, Türkiye, 19 - 22 Mayıs 1999, (Özet Bildiri)
1999
1999117. Asetofenondan türevlenen bazı mono, bis ve katerner Mannich bazlarının sitotoksisitelerinin Brine Shrimp bioassay yöntemi ile saptanması
Gül H. İ., Gül M., Hanninen O.
Serbest Radikaller ve Antioksidanlar Araştırma Derneği II. Ulusal Kongresi, Eskişehir, Türkiye, Eskişehir, Türkiye, 19 - 22 Mayıs 1999, (Özet Bildiri)
Kitaplar
2023
20231. Phenolic Chalcone Mannich Bases and Their Cytotoxic Activity
Gül H. İ.
Current Research in Pharmacy and Pharmaceutical Sciences, Cem Yamalı, Editör, Akademisyen Kitabevi, Ankara, ss.54-67, 2023
2021
20212. İlaç hedefleri olarak enzimler
Gül H. İ., Gül M.
Medisinal Kimya Giriş, Öztekin Algül, Editör, Ankara Nobel Tıp Kitabevleri, Ankara, ss.93-108, 2021
2021
20213. İlaç hedefleri olarak enzimler
GÜL H. İ., GÜL M.
Medisinal Kimya Giriş, Algül Öztekin, Editör, Ankara Nobel Tıp Kitabevleri, Ankara, ss.93-108, 2021
2019
20194. Kanser kemoterapisi
Gül H. İ.
Foye Medisinal Kimya Temel İlkeleri, Öztekin Algül,Kayhan Bolelli, Editör, Ankara Nobel Tıp Kitabevleri, Ankara, ss.513-558, 2019
Desteklenen Projeler
2022 - 2024
2022 - 2024PİRAZOLBENZENSÜLFONAMIT ÇEKiRDEĞI TAŞIYAN POTANSiYEL ANTiKANSER ETKiLi BiLEŞiKLERiN SENTEZi YAPILARININ AYDINLATILMASI VE SiTOTOKSiK AKTiViTELERi -2
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
GÜL H. İ. (Yürütücü)
2021 - 2022
2021 - 2022Sülfonamid artığı taşıyan yeni pirazol türevlerinin sentezi ve sitotoksik etkilerinin araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
GÜL H. İ. (Yürütücü), ÖZMEN ÖZGÜN D.
2021 - 2021
2021 - 2021Tiyazolidinon farmakoforu içeren yeni antidiyabetik ilaç aday adayı bileşiklerin sentez ve biyoaktivite çalışması
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
TUĞRAK M. (Yürütücü), GÜL H. İ., GÜL M.
2020 - 2020
2020 - 2020Triazen Yapısındakii Yeni Sülfonamit Türevi Moleküllerin Sentezi ve Karbonik Anhidraz İnhibisyon Potansiyellerinin Araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
BİLGİNER S. (Yürütücü), GÜLÇİN İ., GÜL H. İ., ANIL B.
2017 - 2020
2017 - 2020PIRAZOL-BENZENSÜLFONAMIT ÇEKIRDEĞI TAŞIYAN POTANSIYEL ANTIKANSER ETKILI BILEŞIKLERIN SENTEZI, YAPILARININ AYDINLATILMASI VE SITOTOKSIK AKTIVITELERI
Yükseköğretim Kurumları Destekli Proje , BAP Diğer
GÜL H. İ. (Yürütücü), YAMALI C.
2018 - 2019
2018 - 20192-(3-(4-Metoksifenil)-5-Aril-4,5-Dihidropirazol-1-Il)Benzo[D]Tiyazol Kimyasal Yapısına Sahip Bileşiklerin Sentezi Ve Mao Enzimi Üzerindeki İnhibe Edici Etkilerinin Araştırılması
TÜBİTAK Projesi
TUĞRAK M., GÜL H. İ. (Yürütücü)
2016 - 2018
2016 - 20182-İNDANON'UN ÇİFT TARAFLI ŞALKON ANALOGLARININ SENTEZİ, YAPI AYDINLATMASI VE SİTOTOKSİK ETKİLERİNİN ARAŞTIRILMASI
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
METE E. (Yürütücü), GÜL H. İ.
2016 - 2017
2016 - 2017"Fenotiyazin halkası taşıyan şalkon türevlerinin tasarımı, sentezi ve sitotoksik aktivitelerinin araştırılması."
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
GÜL H. İ. (Yürütücü), YAMALI C., GÜNEŞAÇAR G.
2016 - 2017
2016 - 2017"2(3H)-BENZOKSAZOLON HALKASI TAŞIYAN ŞALKON YAPISINDAKİ BİLEŞİKLERİN TASARIMI, SENTEZİ VE SİTOTOKSİK ETKİLERİNİN ARAŞTIRILMASI"
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
BİLGİNER S. (Yürütücü), GÜL H. İ.
2015 - 2017
2015 - 20174-[3-(DİFLOROFENİL)-5-(DİMETOKSİFENİL)-4,5-DİHİDRO-1H-PİRAZOL-1-İL]BENZENSÜLFONAMİD TÜREVLERİNİN SENTEZİ VE KARBONİK ANHİDRAZ İNHİBİSYON AKTİVİTELERİNİN ARAŞTIRILMASI
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
GÜL H. İ. (Yürütücü), YAMALI C.
2015 - 2016
2015 - 2016"YENİ FENOLİK BİS-MANNİCH BAZLARININ TASARIMI, SENTEZİ VE SİTOTOKSİK AKTİVİTELERİNİN ARAŞTIRILMASI"
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
GÜL H. İ. (Yürütücü), YAMALI C.
2015 - 2016
2015 - 20164 (3-Substitüefenil-2 -Tiyenil -5 -Trimetoksifenil -4, 5-Dihidro-1H-Pirazol-1-ilBenzensülfonamit Taşıyan Bileşiklerin Tasarımı Sentezi Sitotoksisite ve Karbonik Anhidraz Inhibisyon Etkilerinin Araştırılması
TÜBİTAK Projesi
GÜL H. İ. (Yürütücü)
2012 - 2013
2012 - 20131-FENİL-3-(P-SUBSTİTÜEFENİL)-5-(P-HİDROKSİFENİL)-2-PİRAZOLİN TİPİ BİLEŞİKLERİN SENTEZİ VE KARBONİK ANHİDRAZ İNHİBİSYONU ETKİLERİNİN ARAŞTIRILMASI
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
GÜL H. İ. (Yürütücü)
2012 - 2013
2012 - 2013ECZACILIK FAKÜLTESİ ÇAĞDAŞ EĞİTİM VE ARAŞTIRMA KÜTÜPHANESİ,ASETOFENON TÜREVİ BAZI ŞALKONLARIN SENTESİ VESPEKTRAL YAPI AYDINLATMALARI VE ANTİKANSER ETKİLERİNİN ENZİMLER ÜZERİNE ARAŞTIRILMASI
Yükseköğretim Kurumları Destekli Proje , BAP Güdümlü
GÜL H. İ. (Yürütücü)
2011 - 2013
2011 - 20131-İzopropil-3-aroil-4-aril-4-piperidinol tipi bileşiklerin konvansiyonel ve mikrodalga yöntemi ile sentezi ve biyoaktivitelerinin araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Gül H. İ. (Yürütücü), Mete E.
2011 - 2013
2011 - 20131-İZOPROPİL-3-AROİL-4-ARİL-4-PİPEDİNOL TİPİ BİLEŞİKLERİN KONVANSİYONEL VE MİKRODALGA YÖNTEMİ İLE SENTEZİ VE BİYOAKTİVİTELERİNİN ARAŞTIRILMASI
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
GÜL H. İ. (Yürütücü)
2011 - 2012
2011 - 2012ANTİKANSER ETKİLİ DOĞAL VE SENTETİK BİLEŞİKLERİN VE ETKİ MEKANİZMALARININ ARAŞTIRILMASI
Yükseköğretim Kurumları Destekli Proje , BAP Güdümlü
GÜL H. İ. (Yürütücü)
2010 - 2012
2010 - 2012MİKRODALGA YÖNTEMİ İLE SENTEZ
Yükseköğretim Kurumları Destekli Proje , BAP Güdümlü
GÜL H. İ. (Yürütücü), TUĞRAK M.
2009 - 2011
2009 - 20112-Dietilaminometil-1 -(substituted)fenil-2-propen-1-on kimyasal yapısına sahip bileşiklerin sentezi ve antikandidal aktivitelerinin araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Mete E. (Yürütücü), Gül H. İ.
2008 - 2009
2008 - 20092-Dimetilaminometil-1-aril-2-propen-1-on kimyasal yapısına sahip bileşiklerin sentezi ve antifungal etkisinin araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Gül H. İ. (Yürütücü), Mete E.
2007 - 2009
2007 - 20093-Fenetilamino-1-aril-1 propanon hidroklorür ve 1-fenetil-3 aroil-4 aril-4 piperidinol kimyasal yapısına sahip sentezlenmiş bileşiklerin topoizomeraz enzimi üzerine etkilerinin araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Gül H. İ. (Yürütücü), Mete E.
2007 - 2009
2007 - 2009N,N'-bis (3-dimetilamino-1-aril-propilidene) hidrazindihidroklorürlerin sentezi ve Jurkat hücrelerine karşı sitotoksitelerinin araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Gül H. İ. (Yürütücü), Mete E.
2006 - 2008
2006 - 20083-Fenetilamino-1-aril-1-propanon hidroklorür ve 1-Fenetil-3-aroil-4-aril-4-piperidinol hidroklorür kimyasal yapısına sahip bileşiklerin sentezi ve antifungal etkilerinin araştırılması
Yükseköğretim Kurumları Destekli Proje , BAP Araştırma Projesi
Gül H. İ. (Yürütücü), Mete E.
Bilimsel Dergilerdeki Faaliyetler
2022 - Devam Ediyor
2022 - Devam EdiyorInternational Journal of PharmATA
Danışma Kurul Üyesi
Bilimsel Kuruluşlardaki Üyelikler / Görevler
2018 - Devam Ediyor
2018 - Devam EdiyorTürk Medisinal Kimya Derneği
Üye
Bilimsel Yayınlarda Hakemlikler
Mart 2021
Mart 2021EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
SCI-E Kapsamındaki Dergi
Mayıs 2020
Mayıs 2020BIOORGANIC CHEMISTRY
SCI-E Kapsamındaki Dergi
Nisan 2020
Nisan 2020BIOORGANIC CHEMISTRY
SCI-E Kapsamındaki Dergi
Nisan 2020
Nisan 2020BIOORGANIC CHEMISTRY
SCI-E Kapsamındaki Dergi
Mart 2020
Mart 2020BIOORGANIC CHEMISTRY
SCI-E Kapsamındaki Dergi
Mart 2020
Mart 2020BIOORGANIC CHEMISTRY
SCI-E Kapsamındaki Dergi
Şubat 2020
Şubat 2020BIOORGANIC CHEMISTRY
SCI-E Kapsamındaki Dergi
Aralık 2019
Aralık 2019EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
SCI-E Kapsamındaki Dergi
Aralık 2019
Aralık 2019EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
SCI-E Kapsamındaki Dergi
Ağustos 2019
Ağustos 2019EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
SCI-E Kapsamındaki Dergi
Kasım 2016
Kasım 2016ARABIAN JOURNAL OF CHEMISTRY
SCI-E Kapsamındaki Dergi
Haziran 2015
Haziran 2015ARABIAN JOURNAL OF CHEMISTRY
SCI-E Kapsamındaki Dergi
Mart 2015
Mart 2015ARABIAN JOURNAL OF CHEMISTRY
SCI-E Kapsamındaki Dergi
Temmuz 2014
Temmuz 2014JOURNAL OF MOLECULAR STRUCTURE
SCI-E Kapsamındaki Dergi
Ocak 2014
Ocak 2014Medicinal Chemistry Research
SCI Kapsamındaki Dergi
Ocak 2012
Ocak 2012Journal Of Enzyme Inhibition And Medicinal Chemistry
SCI Kapsamındaki Dergi
Etkinlik Organizasyonlarındaki Görevler
Ekim 2023
Ekim 2023FARMAKON2023 Eczacılık Öğrenci Kongresi
Bilimsel Kongre / Sempozyum Organizasyonu
Aydın A. S., GÜL H. İ.
Erzurum, Türkiye
Kongre ve Sempozyum Katılımı Faaliyetleri
01 Mayıs 2018 - 01 Mayıs 2018
01 Mayıs 2018 - 01 Mayıs 20183rd Internatıonal Conference Onadvances Innatural Applied Scıenceıcanas
Katılımcı
-Türkiye
01 Şubat 2017 - 01 Şubat 2017
01 Şubat 2017 - 01 Şubat 2017The International Workshop on the Application of NMR in Pharmaceutics, Phytotherapeutics and Medicin
Katılımcı
İstanbul-Türkiye
Atıflar
Toplam Atıf Sayısı (WOS): 3379
h-indeksi (WOS): 35
Jüri Üyelikleri
Aralık-2022
Aralık 2022Tez Savunma (Doktora)
Hayati Okur Doktora Tez Savunması > - Ege Üniversitesi
Eylül-2022
Eylül 2022